Year 2022 / Volume 114 / Number 3
Letter
Gruber-Frantz tumor: a rare pancreatic neoplasm

172-173

DOI: 10.17235/reed.2021.8345/2021

Joel Omar Jáquez Quintana, Héctor Jesús Maldonado Garza, Carolina Ivette Zubía-Nevárez,

Abstract
We present the case of a 37-year-old female with abdominal pain in the epigastrium radiating to the right flank of a month of evolution. On physical examination, the epigastric mass was palpated, firm and painless. Computed tomography (CT) showed a cystic tumor in the body and tail of the pancreas with solid areas and defined borders (12 x 10 cm), which displaced structures. Endoscopic ultrasound (EUS)-guided fine needle biopsy was performed, with a cytology consistent with solid pseudopapillary tumor (SPT). Subsequently, a distal pancreatectomy with tumor resection and nodal dissection were performed. Cytology reported discohesive cells, some arranged around capillaries, with small nuclei with clefts, CK7 negative and β-catenin positive. After four years of follow-up, there is no evidence of recurrence.
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References
1. Zalatnai A, Kis-Orha V. Solid-pseudopapillary Neoplasm of Pancreas is still an enigma: a Clinicopathological Review. Pathol Oncol Res. 2020; 26(2): 641-9. Epub 2019 Jun 17. DOI: 10.1007/s12253-019-00671-8.
2. Gandhi D, Sharma P, Parashar K, et al. Solid pseudopapillary Tumor of the Pancreas: Radiological and surgical review. Clin Imaging. 2020; 67:101-7 Epub 2020 Jun 9. DOI: 10.1016/j.clinimag.2020.06.008.
3. La Rosa S, Bongiovanni M. Pancreatic Solid Pseudopapillary Neoplasm: Key Pathologic and Genetic Features. Arch Pathol Lab Med. 2017 Jul;141(7):990-995. DOI: 10.5858/arpa.2016-0322-RS.
4. Milanetto, AC, Gais Zürcher, AL, Macchi, L, et al. Pancreatic solid pseudopapillary neoplasm in male patients: systematic review with three new cases. Updates in Surgery. (2020). DOI: 10.1007/s13304-020-00905-4.
5. Lin X, Lin R, Lu F, et al. Surgical Management of Solid Pseudopapillary Neoplasms of Pancreas: A Single-Center Experience of 60 Patients. Dig Surg. 2020;37(4):348-354. Epub 2020 Jan 20. DOI: 10.1159/000505062.
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Jáquez Quintana J, Maldonado Garza H, Zubía-Nevárez C. Gruber-Frantz tumor: a rare pancreatic neoplasm. 8345/2021


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Publication history

Received: 15/09/2021

Accepted: 11/10/2021

Online First: 25/10/2021

Published: 07/03/2022

Article revision time: 21 days

Article Online First time: 40 days

Article editing time: 173 days


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