Year 2023 / Volume 115 / Number 6
Letter
A retrospective analysis of 32 small and well-differentiated rectal neuroendocrine tumors with regional or distant metastasis

336-337

DOI: 10.17235/reed.2022.9273/2022

Zhijie Wang, Guozhi Yu, Li Li, Shunli Qi, Qian Liu,

Abstract
Rectal neuroendocrine neoplasms (NENs) are a group of rare and heterogeneous diseases and are classified as well-differentiated neuroendocrine tumors (NETs) and poorly differentiated neuroendocrine carcinomas (NECs) based on histological differentiation. The patients were followed up with a median period of 32.5 (range 2-123) months and no patients were lost to follow-up. The median PFS time could not be obtained, as only less than half of the patients suffered tumor progression by the end of follow-up. The 1-year and 3-year PFS rates were 73.5% and 69.2%, respectively. The median OS was 86 months in the entire cohort. The 1-year and 3-year OS rates were 100% and 96.0%, respectively.
Share Button
New comment
Comments
No comments for this article
References
Hrabe J. Neuroendocrine Tumors of the Appendix, Colon, and Rectum. Surg Oncol Clin N Am 2020; 29: 267-279. DOI: 10.1016/j.soc.2019.11.010.
Basuroy R, Haji A, Ramage JK, et al. Review article: the investigation and management of rectal neuroendocrine tumours. Aliment Pharmacol Ther 2016; 44: 332-345. DOI: 10.1111/apt.13697.
Caplin M, Sundin A, Nillson O, et al. ENETS Consensus Guidelines for the management of patients with digestive neuroendocrine neoplasms: colorectal neuroendocrine neoplasms. Neuroendocrinology 2012; 95: 88-97. DOI: 10.1159/000335594.
Anthony LB, Strosberg JR, Klimstra DS, et al. The NANETS consensus guidelines for the diagnosis and management of gastrointestinal neuroendocrine tumors (nets): well-differentiated nets of the distal colon and rectum. Pancreas 2010; 39: 767-774. DOI: 10.1097/MPA.0b013e3181ec1261.
Related articles

Letter

Ileal metastasis from phyllodes breast tumor

DOI: 10.17235/reed.2023.9958/2023

Digestive Diseases Image

Dysphagia secondary to neuroendocrine carcinoma: a rare esophageal tumor

DOI: 10.17235/reed.2023.9951/2023

Digestive Diseases Image

Enteroenteric intussusception caused by a small bowel metastatic cutaneous melanoma

DOI: 10.17235/reed.2023.9876/2023

Letter

A submucosal lesion of the rectum: an unexpected MALT

DOI: 10.17235/reed.2023.9846/2023

Letter

Surgical indication of type I gastric neuroendocrine tumors

DOI: 10.17235/reed.2023.9681/2023

Letter

Mixed adenoneuroendocrine carcinoma of the gallbladder

DOI: 10.17235/reed.2023.9624/2023

Letter

Carcinoid syndrome and somatostatin analogues

DOI: 10.17235/reed.2023.9525/2023

Digestive Diseases Image

Germ cell tumor with duodenal involvement: a rare case of gastrointestinal bleeding

DOI: 10.17235/reed.2022.9327/2022

Letter

Histiocytic sarcoma of the esophagus

DOI: 10.17235/reed.2022.9296/2022

Letter

Vaginal lesion as first manifestation of colorectal disease

DOI: 10.17235/reed.2022.9270/2022

Digestive Diseases Image

Intrabiliary metastasis of colorectal adenocarcinoma: the SPY perspective

DOI: 10.17235/reed.2022.9202/2022

Digestive Diseases Image

The sentinel polyp: high-grade sarcoma revealed after colonic polypectomy

DOI: 10.17235/reed.2022.9093/2022

Digestive Diseases Image

Metastatic lesion of a choroidal melanoma located in the head of pancreas

DOI: 10.17235/reed.2022.8843/2022

Letter

Ectopic ACTH syndrome in a patient with Crohn’s disease

DOI: 10.17235/reed.2022.8825/2022

Digestive Diseases Image

Ileal neuroendocrine tumor as an uncommon cause of obscure gastrointestinal bleeding

DOI: 10.17235/reed.2022.8641/2022

Letter

Pancreatic lipoma: diagnostic boom of a rare mesenchymal tumor

DOI: 10.17235/reed.2022.8536/2021

Letter

Brunneroma: an infrequent duodenal neoplasm

DOI: 10.17235/reed.2021.8349/2021

Letter

Gruber-Frantz tumor: a rare pancreatic neoplasm

DOI: 10.17235/reed.2021.8345/2021

Digestive Diseases Image

Endoscopic resection of a duodenal neuroendocrine tumor

DOI: 10.17235/reed.2021.8232/2021

Digestive Diseases Image

Malignancy of intraductal papillary neoplasm of the bile duct

DOI: 10.17235/reed.2021.8193/2021

Digestive Diseases Image

Imaging findings of melanoma metastasis in the gallbladder

DOI: 10.17235/reed.2021.8176/2021

Letter

Primary Ewing's sarcoma of the small intestine

DOI: 10.17235/reed.2021.7735/2020

Digestive Diseases Image

Inflammatory pseudotumor-like follicular dendritic cell sarcoma of the liver

DOI: 10.17235/reed.2020.7602/2020

Original

Can we optimize CEA as a response marker in rectal cancer?

DOI: 10.17235/reed.2020.7321/2020

Editorial

Colorectal endoscopic submucosal dissection is here to stay

DOI: 10.17235/reed.2020.6960/2020

Letter

Medullary colorectal carcinoma. Do we really know it?

DOI: 10.17235/reed.2020.6728/2019

Digestive Diseases Image

A rare cause of extrahepatic biliary tract stricture: a neuroendocrine carcinoma

DOI: 10.17235/reed.2020.6491/2019

Digestive Diseases Image

Metastatic melanoma of the gallbladder: an uncommon finding

DOI: 10.17235/reed.2020.6407/2019

Letter

Klatskin-mimicking neuroendocrine tumor

DOI: 10.17235/reed.2019.6382/2019

Editorial

Safe surgery for cystic tumors of the pancreas

DOI: 10.17235/reed.2019.6042/2018

Letter to the Editor

Author´s reply: Cystic pancreatic neuroendocrine tumors. A diagnostic challenge

DOI: 10.17235/reed.2018.5415/2017

Letter to the Editor

A case of a mixed adenoneuroendocrine tumor of the colon

DOI: 10.17235/reed.2017.5008/2017

Letter to the Editor

Neuroendocrine tumors of the pancreas: keys issues in dealing with heterogeneity

DOI: 10.17235/reed.2017.4997/2017

Letter to the Editor

Pancreatic neuroendocrine tumors. Prognostic factors

DOI: 10.17235/reed.2017.5109/2017

Letter to the Editor

Sternal cutaneous metastasis of hilar cholangiocarcinoma

DOI: 10.17235/reed.2017.4979/2017

Digestive Diseases Image

Metastasis of dermatofibrosarcoma diagnosed by capsule endoscopy

DOI: 10.17235/reed.2018.4900/2017

Letter to the Editor

Chronic diarrhea, weight loss and heart failure. Features of the same disease?

DOI: 10.17235/reed.2017.4874/2017

Letter to the Editor

A rectal neuroendocrine neoplasm

DOI: 10.17235/reed.2017.4836/2017

Letter to the Editor

A rare cause of intestinal bleeding: duodenal metastasis from endometrial cancer

DOI: 10.17235/reed.2017.4822/2017

Letter to the Editor

Utility of neoadjuvant therapy in rectal GIST

DOI: 10.17235/reed.2017.4751/2016

Letter to the Editor

Pancreatic neuroendocrine tumors

DOI: 10.17235/reed.2017.4725/2016

Editorial

Pancreas neuroendocrine tumors - not so rare or benign

DOI: 10.17235/reed.2016.4672/2016

Digestive Diseases Image

Debut of an unusual liver cirrhosis

Digestive Diseases Image

Intrauterine device in the rectal cavity

Letter to the Editor

Liver metastasis from colorectal cancer 12 years after liver transplantation

DOI: 10.17235/reed.2017.4507/2016

Letter to the Editor

Unusual presentation of obstructive jaundice

DOI: 10.17235/reed.2017.4501/2016

Letter to the Editor

Sister Mary Joseph’s nodule as initial pancreatic cancer manifestation

DOI: 10.17235/reed.2016.4479/2016

Letter to the Editor

Rectal neuroendocrine neoplasia: a rare tumour

DOI: 10.17235/reed.2016.4351/2016

Case Report

Hemobilia due to intracholecystic papillary neoplasm

DOI: 10.17235/reed.2016.4205/2016

Case Report

Mesenteric schwannoma: an unusual cause of abdominal mass

DOI: 10.17235/reed.2016.4202/2016

Letter to the Editor

Gastric neuroendocrine tumor presenting with gastrointestinal bleeding

DOI: 10.17235/reed.2015.3998/2015

Letter to the Editor

Surgical management of appendiceal adenocarcinoid. Case report and literature review

DOI: 10.17235/reed.2016.4049/2015

Case Report

Primary squamous cell carcinoma of the rectum: an atypical histology

DOI: 10.17235/reed.2016.3975/2015

Case Report

Primary esophageal melanoma: report of a case

DOI: 10.17235/reed.2016.3908/2015

Letter to the Editor

Mucinous hepatic cystic neoplasm: An uncommon cystic lesion in the liver

DOI: 10.17235/reed.2015.3698/2015

Letter to the Editor

Duodenal involvement by seminomatous tumors

DOI: 10.17235/reed.2015.3646/2014

Letter to the Editor

Leiomyosarcoma of the ascending colon: a rare tumor with poor prognosis

DOI: 10.17235/reed.2015.3606/2014

Case Report

Malignant degeneration of rectal endometriosis

DOI: 10.17235/reed.2015.3648/2014

Letter to the Editor

Leiomyoma of the round ligament of the liver: Report of one case

DOI: 10.17235/reed.2015.3725/2014

Citation tools
Wang Z, Yu G, Li L, Qi S, Liu Q. A retrospective analysis of 32 small and well-differentiated rectal neuroendocrine tumors with regional or distant metastasis. 9273/2022


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 940 visits.
This article has been downloaded 55 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 10/10/2022

Accepted: 18/10/2022

Online First: 25/10/2022

Published: 06/06/2023

Article Online First time: 15 days

Article editing time: 239 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology