Year 2024 / Volume 116 / Number 1
Letter
Mixed adenoneuroendocrine carcinoma of the gallbladder

48-49

DOI: 10.17235/reed.2023.9624/2023

Qi Wang, Lixia Li, Jun Li, Wanfeng Fan,

Abstract
A 58-year-old woman presented with a 1-day history of abdominal pain. Abdominal CT showed an oval soft tissue density mass in the fundus of the gallbladder (red arrow), approximately 4.0 cm × 3.0 cm in size. The level of cancer antigen 199 was elevated (275.80 U/mL; normal level, 0.0-27.0 U/mL). Other tumor markers were normal including alpha fetoprotein, carcinoembryonic antigen. Abdominal magnetic resonance imaging demonstrated the mass with characteristic of mixed signals, containing marked enhanced ingredient (yellow arrow) and poor blood supply ingredient (blue arrow). Radical cholecystectomy, partial liver resection, and regional lymphadenectomy were performed. Pathological examination indicated mixed adenoneuroendocrine carcinoma, with the following immunohistochemistry results: CD56 (+) (Figure 1F), Syn (+) (Figure 1G), CK19 (+) (Figure 1H), CgA (+), MLHL (+), PMS2 (+), MSH2 (+), MSH6 (+), Ki-67 (60%+).
Share Button
New comment
Comments
No comments for this article
References
1. Zhang Z, Zhong D, Feng T, et al. Mixed Adenoneuroendocrine Carcinoma of the Gallbladder. J Gastrointest Surg 2022;26:503-506.
2. Wang H, Xu X, Wu Q, et al. Mixed adenoneuroendocrine carcinoma of the gallbladder with hepatic metastasis: A case report. Asian J Surg 2022;45:2155-2156.
3. Machairas N, Paspala A, Frountzas M, et al. Mixed Adenoneuroendocrine Carcinoma (MANEC) of the Gallbladder: A Systematic Review of Outcomes Following Surgical Management. In Vivo 2019;33:1721-1726.
Related articles

Letter

Acute cholecystitis treated by direct visualization endoscopy

DOI: 10.17235/reed.2023.9432/2022

Digestive Diseases Image

Imaging findings of melanoma metastasis in the gallbladder

DOI: 10.17235/reed.2021.8176/2021

Digestive Diseases Image

Metastatic melanoma of the gallbladder: an uncommon finding

DOI: 10.17235/reed.2020.6407/2019

Case Report

Pancreatobiliary maljunction: association with gallbladder cancer

DOI: 10.17235/reed.2019.6127/2018

Letter

Subtotal cholecystectomy versus cholecystostomy

DOI: 10.17235/reed.2018.5845/2018

Case Report

Hemobilia due to intracholecystic papillary neoplasm

DOI: 10.17235/reed.2016.4205/2016

Digestive Diseases Image

Porcelain gallbladder

Letter to the Editor

Giant biloma as a result of a blunt abdominal trauma: A case report

DOI: 10.17235/reed.2015.3886/2015

Citation tools
Wang Q, Li L, Li J, Fan W. Mixed adenoneuroendocrine carcinoma of the gallbladder. 9624/2023


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 961 visits.
This article has been downloaded 37 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 27/03/2023

Accepted: 28/03/2023

Online First: 19/04/2023

Published: 11/01/2024

Article Online First time: 23 days

Article editing time: 290 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology