Year 2019 / Volume 111 / Number 7
Case Report
Pancreatobiliary maljunction: association with gallbladder cancer

568-570

DOI: 10.17235/reed.2019.6127/2018

Marta Garzón Benavides, Andrea Núñez Ortiz, Teófilo López Ruiz, Carmen Cepeda Franco, Lourdes Gómez Izquierdo,

Abstract
Background: Pancreatobiliary maljunction is a rare disease characterized by the junction of the pancreatic and biliary ducts outside of the duodenal wall, which normally results in a large common duct. As a result, there is a greater risk of acute pancreatitis and cancer of the gallbladder and biliary tract. Case report: We present the case of a 43-year-old female diagnosed with a pancreatobiliary maljunction and an associated stenosis of the bile duct, secondary to an episode of acute pancreatitis. She underwent several endoscopic retrograde cholangiopancreatography procedures over the course of three years, without improvement of the stenosis, and therefore a surgical approach was taken. Prior to the surgical intervention, magnetic resonance imaging showed the presence of an 11-mm polyp in the gallbladder. A histological study of the surgical sample identified intramucosal adenocarcinoma over a tubular adenoma of the gallbladder. Discussion: Pancreatobiliary maljunction can be considered as a premalignant entity due to the risk of developing cancer of the biliary tree and gallbladder. Therefore, these patients should undergo a prophylactic intervention, despite being asymptomatic.
Share Button
New comment
Comments
No comments for this article
References
2. Kamisawa T, Egawa N, Kakajima H, et al. Origin of the long common cannel base on pancreatographic findings in pancreaticobiliary maljunction. Dig Liver Dis 2005;37:363-367
3. Kamisawa T, Takuma K, Itokawa F, Itoi T. Endoscopic diagnosis of pancreaticobiliary maljunction. World J Gastrointest Endosc 2011; 3(1):1-5
4. Kamisawa T, Honda G, Kurata M, Tokura M, Tsuruta K. Pancreatobiliary Disorders Associated with Pancreatobiliary Maljunction. Dig Surg 2010; 27: 100-04.
5. Davenport M, Stringer MD, Howard ER. Biliary amilylase and congenital choledochal dilatation. J Pediatr Surg 1995;30:474-77
6.Kamisawa T, Ando H, Suyama M, et al. Japanese clinical practice for pancreatobiliary maljunction. J Gastroenterol 2012; 47:731-59.
7. Tashiro S, Imaizumi T, Ohkawa H, Okada A, Katoh T, Kawaharada Y, et al. Pancreaticobiliary maljunction: retrospective and nationwide survey in Japan. J Hepatobiliary Pancreat Surg. 2003; 10:345-51
8. Kamisawa T, Kuruma S, Chiba K, Tabata T, Koizumo S, Kikuyama M. Biliary carcinogenesis in pancreaticobiliary maljunction. J Gastroenterol 2017; 52: 158-63
9. Ohuchida J, Chijiiwa K, Hiyoshi M, Kobayashi K, Konomi H, Tanaka M. Long-term results of treatment for pancreaticobiliary maljunction without bile duct dilatation. Arch Surg 2006;141:1066-70
10. Shimotakahara A, Yamataka A, Yanai T, Kobayashi H, Okazaki T, Lane GJ, et al. Roux-en-Y hepaticojejunostomy or hepaticoduodenostomy for biliary reconstruction during the surgical treatment of choledocahl cyst: which is better?Pediatri Surg Int 2005;21:5-7
1. Kamisawa T, Takuma K, Anjiki H, Egawa N, Kurata M, Honda G, Tsuruta K, Sasaki T. Pancreatobiliary Maljunction. Clin Gastroenterol Hepatol 2009;7:S84-S88
Related articles

Digestive Diseases Image

Traumatic biliary fistula with bile duct disconnection

DOI: 10.17235/reed.2024.10096/2023

Letter

Hematoma post-endoscopic retrograde cholangiopancreatography

DOI: 10.17235/reed.2023.9670/2023

Digestive Diseases Image

Endosonographic and ERCP findings in COVID-19 critical illness cholangiopathy

DOI: 10.17235/reed.2022.9218/2022

Digestive Diseases Image

Cholangiohydatidosis: an uncommon cause of acute cholangitis

DOI: 10.17235/reed.2020.7063/2020

Letter

Obstructive jaundice of a parasitic etiology

DOI: 10.17235/reed.2018.5827/2018

Citation tools
Garzón Benavides M, Núñez Ortiz A, López Ruiz T, Cepeda Franco C, Gómez Izquierdo L. Pancreatobiliary maljunction: association with gallbladder cancer. 6127/2018


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 1087 visits.
This article has been downloaded 173 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 16/12/2018

Accepted: 06/03/2019

Online First: 19/06/2019

Published: 04/07/2019

Article Online First time: 185 days

Article editing time: 200 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2024 y Creative Commons. The Spanish Journal of Gastroenterology