Year 2021 / Volume 113 / Number 5
Digestive Diseases Image
Inflammatory pseudotumor-like follicular dendritic cell sarcoma of the liver

378-379

DOI: 10.17235/reed.2020.7602/2020

Ana Aparicio Serrano, Javier Castro Rodríguez, Elma Gallego Jiménez, Pilar Barrera Baena,

Abstract
A 53-year-old female with a history of HLA-B27 positive polyarthritis underwent a splenectomy due to an incidental splenic lesion, which was confirmed as an inflammatory pseudotumor (IPT). Afterwards, two liver lesions were found and histopathological examination revealed inflammatory pseudotumor-like follicular dendritic cell sarcoma (IPT-like FDCS). The patient received NSAIDs, corticosteroids, antibiotics and azathioprine, with no response. Within the next few months, there was an abrupt clinical worsening due to rapid progression of the hepatic lesions and a massive hepatomegaly. New biopsies were obtained, showing undifferentiated sarcoma. The patient started chemotherapy with doxorubicin and eventually died.
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References
1. Cheuk W, Chan JK, Shek TW, et al. Inflammatory pseudotumor-like follicular dendritic cell tumor: a distinctive low-grade malignant intra-abdominal neoplasm with consistent Epstein-Barr virus association. Am J Surg Pathol 2001;25(6):721-31.
2. Zhang BX, Chen ZH, Liu Y, et al. Inflammatory pseudotumor-like follicular dendritic cell sarcoma: A brief report of two cases. World J Gastrointest Oncol 2019; 11(12): 1231-9.
3. Liu X, Cao L, Chin W, et al. Epstein-Barr virus-negative inflammatory pseudotumor-like variant of follicular dendritic cell sarcoma of the liver: A case report and literature review. Clin Res Hepatol Gastroenterol. 2020 Jun 13:S2210-7401(20)30150-9.
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Aparicio Serrano A, Castro Rodríguez J, Gallego Jiménez E, Barrera Baena P. Inflammatory pseudotumor-like follicular dendritic cell sarcoma of the liver. 7602/2020


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Publication history

Received: 23/10/2020

Accepted: 08/11/2020

Online First: 29/12/2020

Published: 10/05/2021

Article revision time: 13 days

Article Online First time: 67 days

Article editing time: 199 days


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