Year 2024 / Volume 116 / Number 12
Letter
IgG4-related disease mimicking a liver abscess

707-708

DOI: 10.17235/reed.2024.10265/2024

Pere Vaquer-Grimalt, Irene Micaela García, Ester Antón, Aina Escarda, Margalida Vanrell, Lucía Bonet, Lydia Sastre,

Abstract
IgG4-related disease (IGRD) is a complex medical condition affecting multiple organs, including the liver. The condition is characterized by excessive production of IgG4 antibodies, leading to chronic inflammation and tissue damage. We present a case of a 37-year-old man with a history of chronic pancreatitis was diagnosed with a liver mass. Initial treatment included piperacillin and tazobactam, but the patient's condition worsened. An ultrasound-guided biopsy revealed increased IgG4 positive cells, leading to the diagnosis of an inflammatory pseudotumor associated with IGRD. The patient was treated with prednisone taper therapy, and the liver mass resolved after six months of corticoid treatment.
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References
1. Bateman AC, Culver EL. Challenges and pitfalls in the diagnosis of IgG4-related disease. Semin Diagn Pathol. Published online November 15, 2023. doi:10.1053/j.semdp.2023.11.005
2. Umehara H, Okazaki K, Kawa S, et al. The 2020 revised comprehensive diagnostic (RCD) criteria for IgG4-RD. Mod Rheumatol. 2021;31(3):529–33.
3. Deshpande V, Zen Y, Chan JK, et al. Consensus statement on the pathology of IgG4-related disease. Mod Pathol. 2012;25(9):1181-1192. doi:10.1038/modpathol.2012.72
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Vaquer-Grimalt P, García I, Antón E, Escarda A, Vanrell M, Bonet L, et all. IgG4-related disease mimicking a liver abscess. 10265/2024


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Publication history

Received: 13/01/2024

Accepted: 21/01/2024

Online First: 02/02/2024

Published: 13/12/2024

Article Online First time: 20 days

Article editing time: 335 days


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