Year 2016 / Volume 108 / Number 10
Case Report
Primary esophageal melanoma: report of a case

666-669

DOI: 10.17235/reed.2016.3908/2015

Laura Granel Villach, María Amparo Moya Sanz, Carlos Fortea Sanchis, Vicente Javier Escrig Sos, Carlos Fortea Sanchís, Carmen Martínez Lahuerta, Nuria Tornador Gaya, José Luis Salvador Sanchís,

Abstract
Introduction: Primary malignant melanoma of the esophagus is a rare tumor representing only 0.1-0.2% of esophageal malignancies. The goal of the study was to report on the management of a new case diagnosed and treated in our site. Case report: A 67-year-old patient presented with dysphagia to solids with no other remarkable history or associated skin lesions. He underwent gastroscopy, which revealed a polypoid mass suggestive of neoplasm in the distal third of the esophagus. Biopsy indicated melanoma with positive immunohistochemical markers S100 and HMB45, and negative cytokeratins and CEA. Computerized tomography (CT) and positron-emission tomography (PET) scans showed no local infiltration or distant metastases. An Ivor-Lewis esophagectomy procedure was performed with regional lymphadenectomy. Postoperative stay lasted for three weeks, and no remarkable postsurgical complications arose. The pathological study of the specimen confirmed the diagnosis of primary esophageal melanoma. Discussion: Primary malignant melanoma of the esophagus has an unfortunate prognosis as it is an aggressive tumor usually diagnosed at an advanced stage, with local invasion and metastatic disease. Currently, surgery is the treatment of choice, with the remaining adjuvant therapies obtaining limited results.
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Granel Villach L, Moya Sanz M, Fortea Sanchis C, Escrig Sos V, Fortea Sanchís C, Martínez Lahuerta C, et all. Primary esophageal melanoma: report of a case. 3908/2015


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Publication history

Received: 27/06/2015

Accepted: 21/07/2015

Online First: 20/01/2016

Published: 30/09/2016

Article revision time: 20 days

Article Online First time: 207 days

Article editing time: 461 days


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