Year 2024 / Volume 116 / Number 2
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Germ cell tumor with duodenal involvement: a rare case of gastrointestinal bleeding

118-119

DOI: 10.17235/reed.2022.9327/2022

Margarida Gonçalves, Joana Sobreiro Silva, Ana Rebelo,

Abstract
A 19-year-old male presented to the emergency department with a 7-day history of melena, anorexia and asthenia. Blood tests revealed a hemoglobin of 5.8 g/dL. Upper endoscopy showed a large ulcerated and stenosing lesion in the duodenum. The histologic examination of the biopsy specimen showed a neoplasia with epithelioid cells, accentuated atypia and pleomorphism, expressing MNF 116 cytokeratin, CD30, glypican 3 and alpha-fetoprotein on immunohistochemistry, suggesting of a germ cell tumor metastasis.
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21/02/2024 0:32:19
Very interesting case congrats 👏👏👏


References
1- G. S. Rosenblatt, C. J. Walsh, and S. Chung, “Metastatic testis tumor presenting as gastrointestinal hemorrhage,” Journal of Urology, vol. 164, no. 5, p. 1655, 2000.
2- Chait, M. M., Kurtz, R. C. and Hajdu, S. I.: Gastrointestinal tract metastasis in patients with germ-cell tumor of the testis. Am J Dig Dis, 23: 925, 1978. DOI: 10.1007/BF01072468
3- Ma Y, Zhang W, Qiao Z, et al. Endoscopic ultrasound-guided fine-needle aspiration for the diagnosis of a case of a huge abdominal mass. Rev Esp Enferm Dig. 2021 Feb; (2):143-144. DOI: 10.17235/reed.2020.7305/2020
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Gonçalves M, Silva J, Rebelo A. Germ cell tumor with duodenal involvement: a rare case of gastrointestinal bleeding. 9327/2022


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Publication history

Received: 02/11/2022

Accepted: 10/11/2022

Online First: 22/11/2022

Published: 07/02/2024

Article Online First time: 20 days

Article editing time: 462 days


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