Year 2023 / Volume 115 / Number 3
Letter
Glanzmann thrombasthenia: an uncommon cause of acute upper gastrointestinal bleeding

149

DOI: 10.17235/reed.2022.9081/2022

Raúl Alberto Jiménez Castillo, Daniel Eduardo Benavides-Salgado, Joel Omar Jáquez-Quintana, José Alberto González González, Carlos Alejandro Cortez Hernández, Homero Náñez-Terreros, Héctor Jesús Maldonado-Garza,

Abstract
The major function of platelets is to contribute to hemostasis. If an impairment in their production and/or function occurs, abnormal bleeding can develop. An 18-year-old male presented to our hospital after four episodes of hematemesis. His medical history was relevant for Glanzmann thrombasthenia diagnosed during early childhood. On initial examination, he appeared pale and with normal blood pressure. His complete blood count included a hemoglobin concentration of 11.0 g/dL, additional laboratory tests were within the normal ranges. The initial approach consisted of a high dose of proton pump inhibitors. Hours later, esophagogastroduodenoscopy revealed diffuse oozing bleeding from gastric mucosa with no other visible lesions such as peptic ulcers or varices
Share Button
New comment
Comments
No comments for this article
References
1. Diz-Küçükkaya R. Inherited platelet disorders including Glanzmann thrombasthenia and Bernard-Soulier syndrome. Hematology Am Soc Hematol Educ Program. 2013; 2013:268-75.
2. Nurden AT, Pillois X. ITGA2B and ITGB3 gene mutations associated with Glanzmann thrombasthenia. Platelets. 2018; 29:98-101.
3. Franchini M, Favaloro EJ, Lippi G. Glanzmann thrombasthenia: an update. Clin Chim Acta. 2010; 411:1-6.
4. Grainger JD, Thachil J, Will AM. How we treat the platelet glycoprotein defects; Glanzmann thrombasthenia and Bernard Soulier syndrome in children and adults. Br J Haematol. 2018; 182:621-32.
Related articles

Letter

Jejunal gastrointestinal stromal tumor: a diagnostic challenge

DOI: 10.17235/reed.2024.10108/2023

Letter

Blue rubber bleb nevus syndrome

DOI: 10.17235/reed.2023.9913/2023

Letter

Upper gastrointestinal bleeding and Rigler triad

DOI: 10.17235/reed.2023.9731/2023

Digestive Diseases Image

Germ cell tumor with duodenal involvement: a rare case of gastrointestinal bleeding

DOI: 10.17235/reed.2022.9327/2022

Letter

A rare cause of obscure gastrointestinal bleeding

DOI: 10.17235/reed.2022.9156/2022

Letter

Weil syndrome coincident with upper gastrointestinal bleeding

DOI: 10.17235/reed.2022.9086/2022

Letter

A full hemostatic repertoire in a complex cirrhotic patient

DOI: 10.17235/reed.2022.9039/2022

Letter

Hemostasis of a bleeding inverted colonic diverticulum

DOI: 10.17235/reed.2022.9019/2022

Letter

Primary intestinal melanoma?

DOI: 10.17235/reed.2022.8944/2022

Letter

A rare cause of a bulging mass in the mid esophagus

DOI: 10.17235/reed.2022.8834/2022

Digestive Diseases Image

Ileal neuroendocrine tumor as an uncommon cause of obscure gastrointestinal bleeding

DOI: 10.17235/reed.2022.8641/2022

Digestive Diseases Image

Bezoar: an uncommon cause of upper gastrointestinal bleeding

DOI: 10.17235/reed.2021.8311/2021

Letter

COVID-19 and aorto-enteric fistula

DOI: 10.17235/reed.2021.8272/2021

Digestive Diseases Image

Ink stained gastric lesions: a rare cause of gastrointestinal bleeding

DOI: 10.17235/reed.2021.8141/2021

Digestive Diseases Image

Gastric plasmacytoma: a rare cause of upper gastrointestinal bleeding

DOI: 10.17235/reed.2021.7816/2021

Letter to the Editor

Severe obscure gastrointestinal bleeding successfully treated with idarucizumab

DOI: 10.17235/reed.2018.5298/2017

Letter to the Editor

Gangliocytic paraganglioma: an unusual cause of upper gastrointestinal bleeding

DOI: 10.17235/reed.2017.4808/2016

Letter to the Editor

Gastric neuroendocrine tumor presenting with gastrointestinal bleeding

DOI: 10.17235/reed.2015.3998/2015

Case Report

Downhill varices: an uncommon cause of upper gastrointestinal bleeding

DOI: 10.17235/reed.2015.3697/2015

Citation tools
Jiménez Castillo R, Benavides-Salgado D, Jáquez-Quintana J, González González J, Cortez Hernández C, Náñez-Terreros H, et all. Glanzmann thrombasthenia: an uncommon cause of acute upper gastrointestinal bleeding. 9081/2022


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 1257 visits.
This article has been downloaded 94 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 13/07/2022

Accepted: 15/07/2022

Online First: 28/07/2022

Published: 07/03/2023

Article Online First time: 15 days

Article editing time: 237 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology