Year 2017 / Volume 109 / Number 7
Letter to the Editor
Utility of neoadjuvant therapy in rectal GIST

534-535

DOI: 10.17235/reed.2017.4751/2016

Víctor López-López, Juan Ángel Fernández, Pascual Parrilla,

Abstract
Neoadjuvant therapy with Imatinib is the preferred treatment for rectal GISTs in order to reduce the aggressiveness of a surgical resection. At present, surgical resection does not require wide surgical margins. There is also a lot of controversy with regard to the need for a broad anatomical resection or if a local resection is sufficient and maintains maximum oncological safety and minimum morbidity and mortality. We present a case report of a rectal GIST with a good response to neoadjuvant treatment which allowed a transanal resection.
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References
1. Wilkinson MJ, Fitzgerald JE, Strauss DC, et al. Surgical treatment of gastrointestinalstromal tumour of the rectum in the era of imatinib. Br J Surg. 2015; 102: 965-71.
2. Jakob J, Mussi C, Ronellenfitsch U, et al. Gastrointestinal stromal tumor of the rectum: results of surgical and multimodality therapy in the era of imatinib. Ann Surg Oncol 2013; 20: 586-92.
3. Agaimy A, Vassos N, Märkl B,et al. Anorectal gastrointestinal stromal tumors: a retrospective multicenter analysis of 15 cases emphasizing their high local recurrence rate and the need for standardized therapeutic approach. Int J Colorectal Dis 2013; 28: 1057-64.
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López-López V, Fernández J, Parrilla P. Utility of neoadjuvant therapy in rectal GIST . 4751/2016


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Publication history

Received: 23/11/2016

Accepted: 28/11/2016

Online First: 22/05/2017

Published: 30/06/2017

Article Online First time: 180 days

Article editing time: 219 days


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