Year 2025 / Volume 117 / Number 2
Digestive Diseases Image
Gastric heterotopia in the rectum: a rare entity with potential pitfalls

102-103

DOI: 10.17235/reed.2023.9693/2023

André Gonçalves, Diogo Simas, Sandra Barbeiro, Helena Vasconcelos,

Abstract
Gastric heterotopia (GHT) is a medical condition where the gastric mucosa is found at a non-phyysiological part of the body. GHT can present itself anywhere in the gastrointestinal tract from the mouth to the anorectal area, as well as in the hepatobiliary system. However, it is relatively rare to find GHT in the rectum, with only around 50 documented cases reported in medical literature. We present the case of a 51-year-old man who underwent average-risk screening colonoscopy. He had no clinically significant comorbidities and was otherwise asymptomatic, with no family history. Notable findings included a pseudopolypoid lesion in the distal rectum, adjacent to the dentate line, measuring approximately 15 mm with regular-appearing mucosa under narrow-band-imaging. Biopsy specimens showed histological characteristics of oxyntic-type gastric mucosa without inflammation or dysplasia. GHT has the potential to progress to malignancy, although the rate of malignancy is currently unknown. Awareness of this entity is important given its frequency and potential for misdiagnosis.
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Comments

05/02/2025 20:55:45
La resección endoscópica es una buena alternativa para estos casos de GTH con buenos resituados a mediano plazo


References
1. Srinivasan R, Loewenstine H, Mayle JE. Sessile polypoid gastric heterotopia of rectum: a report of 2 cases and review of the literature. Arch Pathol Lab Med 1999; 123(3): 222–224.
2. Iacopini F, Gotoda T, Elisei W, et al. Heterotopic gastric mucosa in the anus and rectum: first case report of endoscopic submucosal dissection and systematic review. Gastroenterol Rep 2016; 4: 196–205.
3. Dinarvand P, Vareedayah AA, Phillips NJ, Hachem C, Lai J. Gastric heterotopia in rectum: A literature review and its diagnostic pitfall. SAGE Open Med Case Rep. 2017 Feb 17;5:2050313X17693968.
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Gonçalves A, Simas D, Barbeiro S, Vasconcelos H. Gastric heterotopia in the rectum: a rare entity with potential pitfalls. 9693/2023


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Publication history

Received: 25/04/2023

Accepted: 02/05/2023

Online First: 12/05/2023

Published: 05/02/2025

Article Online First time: 17 days

Article editing time: 652 days


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The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
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