Year 2019 / Volume 111 / Number 10
Digestive Diseases Image
Intraductal papillary mucinous neoplasm of the biliary tract: a lesion of the bile duct lumen

796-797

DOI: 10.17235/reed.2019.6186/2019

Eugenia Sánchez Rodríguez, Alejandra Caminoa Lizarralde, Jose Ramón Foruny Olcina, Enrique Vázquez Sequeiros,

Abstract
Intraductal papillary neoplasm of the bile duct (IPNB) is a rare entity characterized by papillary growth within the bile duct lumen1, currently regarded as a biliary counterpart of intraductal papillary mucinous neoplasm of the pancreas. The most common clinical findings are abdominal pain, jaundice or cholangitis, although some patients are asyntomatic. The diagnosis requires careful assessment of imaging findings and cito-histological evaluation, with endoscopic ultrasound guided fine needle aspiration (EUS-FNA) playing a very important role. IPNB is a premalignant lesion which can evolve into invasive cholangiocarcinom. A radical treatment strategy should be planned accordingly.
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References
1. Rocha FG, Lee H, Katabi N et al. Intraductal papillary neoplasm of the bile duct: a biliary equivalent to intraductal papillary mucinous neoplasm of the pancreas? Hepatology. 2012;56(4):1352–1360.
2. Nakanuma Y, Zen Y, Harada K et al. Tumorigenesis and phenotypic characteristics of mucin-producing bile duct tumors: an immunohistochemical approach. J Hepatobiliary Pancreat Sci (2010) 17:211–222.
Pérez Saborido B, Bailón Cuadrado M, Rodríguez López M, et al. Intraductal papillary neoplasia of the bile duct with malignancy: a differentiated entity of cholangiocarcinoma with a better prognosis. A review of three new cases. Rev Esp Enferm Dig. 2017 Aug;109(8):592-595. doi: 10.17235/reed.2017.4835/2016.
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Sánchez Rodríguez E, Caminoa Lizarralde A, Foruny Olcina J, Vázquez Sequeiros E. Intraductal papillary mucinous neoplasm of the biliary tract: a lesion of the bile duct lumen. 6186/2019


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Publication history

Received: 21/01/2019

Accepted: 09/02/2019

Online First: 09/09/2019

Published: 03/10/2019

Article revision time: 4 days

Article Online First time: 231 days

Article editing time: 255 days


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