Year 2019 / Volume 111 / Number 8
Case Report
Life-threating diarrhea and acute renal failure secondary to pancreatic VIPoma treated by surgery

641-643

DOI: 10.17235/reed.2019.6244/2019

María Lapeña Rodríguez, Rafael Cholvi Calduch, Elena Muñoz Forner, Marina Garcés Albir, Luis Sabater Ortí,

Abstract
Pancreatic neuroendocrine tumors represent less than 5% of all pancreatic tumors. They are a heterogeneous group of neoplasms with a diverse behavior and prognosis. Pancreatic vasoactive intestinal polypeptide tumor (VIPoma) is an exceptional tumor within this group due to its low incidence. The presence of pancreatic VIPoma should be clinically suspected in all patients with watery diarrhea, particularly when accompanied by a loss of potassium and bicarbonate and a pancreatic mass on imaging. There are other pathologies with similar symptoms; therefore, a correct differential diagnosis with an adequate treatment is essential for its management. We present the case of a 46-year-old patient who developed a prerenal kidney failure secondary to severe watery diarrhea after a diagnosis of pancreatic VIPoma. Thus, a resection was performed as the patient was rapidly deteriorating and required an intervention.
Share Button
New comment
Comments
No comments for this article
References
1. Nikou GC, Toubanakis C, Nikolaou P, et al. VIPomas: an update in diagnosis and management in a series of 11 patients. Hepatogastroenterology. 2005;52:1259-65.
2. Zerbi A, Falconi M, Rindi G, et al. Clinicopathological Features of Pancreatic Endocrine Tumors: A Prospective Multicenter Study in Italy of 297 Sporadic Cases. Am J Gastroenterol. 2010;105:1421-9.
3. Perry RR, Vinik AI. Clinical review 72: diagnosis and management of functioning islet cell tumors. J Clin Endocrinol Metab 1995; 80:2273.
4. Fernández-Bañares, F., Accarino, A., Balboa, A., et al. (2016). Diarrea crónica: definición, clasificación y diagnóstico. Gastroenterología y Hepatología, 39(8), 535-559.
5. Low G, Panu A, Millo N, et al. Multimodality Imaging of the neoplastic and non neoplastic solid lesions of the pancreas. Radiographics. 2011;31:993-1015.
6. Pereira, F. (2018). Pancreas neuroendocrine tumors: not so rare or benign. Revista Espanola de Enfermedades Digestivas, 108(11), 687-688.
7. Partelli S, Gaujoux S, Boninsegna L, et al. Pattern and clinical predictors of lypmh node involvement in nonfunctioning pan- creatic neuroendocrine tumors. JAMA Surg. 2013;148:932-9.
8. He Z, Quian D, Hua J, et al. Clinical comparison of distal pan- createctomy with or without splenectomy: a meta-analysis. PloS One. 2014;9:e91593.
9. Castellano D, Grande E, Valle J, et al. Expert consensus for the management of advanced or metastatic pancreatic neuroendocrine and carci- noid tumors. Cancer Chemother Pharmacol. 2015;75:1099-114
10. Frilling A, Modlin IM, Kidd M et al. Recommendations for management of patients with neuroendocrine liver metastases. Lancet Oncol 2014;15:e8-21
Related articles

Digestive Diseases Image

Imaging of pancreatic desmoid fibromatosis by endoscopic ultrasound

DOI: 10.17235/reed.2023.9792/2023

Letter

Surgical indication of type I gastric neuroendocrine tumors

DOI: 10.17235/reed.2023.9681/2023

Letter

Carcinoid syndrome and somatostatin analogues

DOI: 10.17235/reed.2023.9525/2023

Letter

Lymphocytic colitis with macroscopic findings

DOI: 10.17235/reed.2023.9497/2023

Digestive Diseases Image

Whipple’s disease – A typical endoscopic finding of a rare disease

DOI: 10.17235/reed.2022.9338/2022

Letter

Diarrhea and monkeypox: a consideration

DOI: 10.17235/reed.2022.8957/2022

Digestive Diseases Image

An unusual cause of a protuberant lesion of the gastric antrum

DOI: 10.17235/reed.2022.8771/2022

Letter

Pancreatic lipoma: diagnostic boom of a rare mesenchymal tumor

DOI: 10.17235/reed.2022.8536/2021

Letter

Gruber-Frantz tumor: a rare pancreatic neoplasm

DOI: 10.17235/reed.2021.8345/2021

Digestive Diseases Image

Endoscopic resection of a duodenal neuroendocrine tumor

DOI: 10.17235/reed.2021.8232/2021

Digestive Diseases Image

Villous atrophy, an endoscopic and diagnostic challenge

DOI: 10.17235/reed.2021.8169/2021

Digestive Diseases Image

Gastroduodenal Burkitt’s lymphoma: a rare cause of epigastric pain and diarrhea

DOI: 10.17235/reed.2021.8150/2021

Original

Chronic diarrhea due to autoimmune enteropathy

DOI: 10.17235/reed.2020.7218/2020

Letter

An uncommon cause of chronic abdominal pain and diarrhea

DOI: 10.17235/reed.2020.6657/2019

Digestive Diseases Image

A rare cause of extrahepatic biliary tract stricture: a neuroendocrine carcinoma

DOI: 10.17235/reed.2020.6491/2019

Letter

Pancreatic panniculitis

DOI: 10.17235/reed.2019.6116/2018

Digestive Diseases Image

Intraductal papillary mucinous neoplasm of the main duct in a patient with pancreas divisum

DOI: 10.17235/reed.2019.5959/2018

Letter

Keriorrhea (waxy diarrhea), a new sign to bear in mind

DOI: 10.17235/reed.2018.5614/2018

Letter to the Editor

Author´s reply: Cystic pancreatic neuroendocrine tumors. A diagnostic challenge

DOI: 10.17235/reed.2018.5415/2017

Letter to the Editor

Ectopic pancreas: a very unusual intestinal mass

DOI: 10.17235/reed.2017.5353/2017

Letter to the Editor

Neuroendocrine tumors of the pancreas: keys issues in dealing with heterogeneity

DOI: 10.17235/reed.2017.4997/2017

Letter to the Editor

Pancreatic neuroendocrine tumors. Prognostic factors

DOI: 10.17235/reed.2017.5109/2017

Letter to the Editor

Pancreatic neuroendocrine tumors

DOI: 10.17235/reed.2017.4725/2016

Editorial

Pancreas neuroendocrine tumors - not so rare or benign

DOI: 10.17235/reed.2016.4672/2016

Letter to the Editor

Diarrhea caused by multiparasitic infection

DOI: 10.17235/reed.2016.4100/2015

Citation tools
Lapeña Rodríguez M, Cholvi Calduch R, Muñoz Forner E, Garcés Albir M, Sabater Ortí L. Life-threating diarrhea and acute renal failure secondary to pancreatic VIPoma treated by surgery. 6244/2019


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 1031 visits.
This article has been downloaded 177 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 20/02/2019

Accepted: 29/03/2019

Online First: 24/06/2019

Published: 31/07/2019

Article Online First time: 124 days

Article editing time: 161 days


Share
This article has been rated by 1 readers.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology