Year 2016 / Volume 108 / Number 2
Original
Irritable bowel syndrome subtypes: Clinical and psychological features, body mass index and comorbidities

59-64

DOI: 10.17235/reed.2015.3979/2015

Cristiane Kibune Nagasako, Ciro Garcia Montes, Sônia Letícia Silva Lorena, Maria Aparecida Mesquita,

Abstract
Background: Irritable bowel syndrome (IBS) is classified into subtypes according to bowel habit. Objective: To investigate whether there are differences in clinical features, comorbidities, anxiety, depression and body mass index (BMI) among IBS subtypes. Methods: The study group included 113 consecutive patients (mean age: 48 ± 11 years; females: 94) with the diagnosis of IBS. All of them answered a structured questionnaire for demographic and clinical data and underwent upper endoscopy. Anxiety and depression were assessed by the Hospital Anxiety and Depression scale (HAD). Results: The distribution of subtypes was: IBS-diarrhea (IBS-D), 46%; IBS-constipation (IBS-C), 32%, and mixed IBS (IBS-M), 22%. IBS overlap with gastroesophageal reflux disease (GERD), functional dyspepsia, chronic headache and fibromyalgia occurred in 65.5%, 48.7%, 40.7% and 22.1% of patients, respectively. Anxiety and/or depression were found in 81.5%. Comparisons among subgroups showed that bloating was significantly associated with IBS-M compared to IBS-D (odds ratio-OR-5.6). Straining was more likely to be reported by IBS-M (OR 15.3) and IBS-C (OR 12.0) compared to IBS-D patients, while urgency was associated with both IBS-M (OR 19.7) and IBS-D (OR 14.2) compared to IBS-C. In addition, IBS-M patients were more likely to present GERD than IBS-D (OR 6.7) and higher scores for anxiety than IBS-C patients (OR 1.2). BMI values did not differ between IBS-D and IBS-C. Conclusion: IBS-M is characterized by symptoms frequently reported by both IBS-C (straining) and IBS-D (urgency), higher levels of anxiety, and high prevalence of comorbidities. These features should be considered in the clinical management of this subgroup.
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Kibune Nagasako C, Garcia Montes C, Silva Lorena S, Mesquita M. Irritable bowel syndrome subtypes: Clinical and psychological features, body mass index and comorbidities. 3979/2015


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Publication history

Received: 20/08/2015

Accepted: 15/11/2015

Online First: 30/11/2015

Published: 01/02/2016

Article revision time: 85 days

Article Online First time: 102 days

Article editing time: 165 days


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