Year 2021 / Volume 113 / Number 6
Letter
Effectiveness of almagate in gastroesophageal reflux disease: a post-hoc analysis of a randomized cross-over double-blind study

479

DOI: 10.17235/reed.2020.7449/2020

Fermín Mearin, Francesca Pajuelo Lorenzo, José Ríos,

Abstract
Almagate (aluminium-magnesium hydroxycarbonate hydrate) is a widely used antacid in Spain as an over-the-counter formulation. However, data on the control of acidity in patients with gastroesophageal reflux disease (GERD) are scarce. Herein we report a post-hoc analysis of a randomized crossover double-blind trial (ALR-006; data on file), in which equivalent single oral doses (1.5 g) of two formulations of almagate (AlmaxRetard® and Almax®, Laboratorios Almirall, Barcelona, Spain) were both effective for reflux esophagitis.
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25/01/2022 7:47:01
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References
1. Rey E, Poves-Francés C, Sánchez G, et al. Effects of effervescent ranitidine on gastric pH: comparison with almagate and placebo in fasting and postprandial conditions. Aliment Pharmacol Ther 2004;20:683-8.
2. IQVIA. TAM. July 2020.
Citation tools
Mearin F, Pajuelo Lorenzo F, Ríos J. Effectiveness of almagate in gastroesophageal reflux disease: a post-hoc analysis of a randomized cross-over double-blind study. 7449/2020


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Publication history

Received: 30/07/2020

Accepted: 27/09/2020

Online First: 03/12/2020

Published: 04/06/2021

Article revision time: 27 days

Article Online First time: 126 days

Article editing time: 309 days


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