Year 2021 / Volume 113 / Number 10
Letter
Leflunomide as a cause of collagenous colitis: an entity to consider

735

DOI: 10.17235/reed.2021.8015/2021

Paulina Núñez, Rodrigo Quera, Lilian Flores, Luis Contreras,

Abstract
Leflunomide belongs in the group of disease-modifying anti-rheumatic drugs (DMARDs) used in the treatment of psoriatic, rheumatoid, and reactive arthritis. Approximately 20 % of patients will experience some adverse event, mainly weight loss, abdominal pain, and diarrhea. We describe the clinical, endoscopic, and histological findings in a patient with psoriatic arthritis (PA) who developed severe chronic diarrhea after drug use.
Share Button
New comment
Comments
No comments for this article
References
1. Verschueren P, Vandooren AK, Westhovens R. Debilitating diarrhea and weight loss due to colitis in two RA patients treated with leflunomide. Clin Rheumatol 2005; 24: 87-90
2. Gugenberger C, Donner P, Maami A, et al. Pesistent diarrhea and loss of weight during therapy with leflunomide. Dtsch Med Wochenschr 2008;133:1730-2
3. Kwok AMF, Morosin T. Leflunomide-induced colitis in association with enterocutaneous fistula in an immunosuppressed patient with renal and rheumatoid arthritis. J gastroenterol 2019;12:310-5. doi: 10.1007/s12328-019-00954-2
Citation tools
Núñez P, Quera R, Flores L, Contreras L. Leflunomide as a cause of collagenous colitis: an entity to consider . 8015/2021


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 1362 visits.
This article has been downloaded 209 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 02/04/2021

Accepted: 10/04/2021

Online First: 19/04/2021

Published: 06/10/2021

Article Online First time: 17 days

Article editing time: 187 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2024 y Creative Commons. The Spanish Journal of Gastroenterology