Year 2017 / Volume 109 / Number 2
Case Report
Management of pancreatic gastrinoma associated with Von Hippel-Lindau disease: a case report

154-157

DOI: 10.17235/reed.2016.4224/2016

Ángela Sala Hernández, Eva María Montalvá Orón, Eugenia Pareja Ibars, Neus Ballester Pla, Rafael López Andújar,

Abstract
Background: Pancreatic neuroendocrine tumors (PNET) are a heterogeneous group and constitute 1.3% of all pancreatic tumors. Approximately 10% of these occur in the context of hereditary syndromes, such as VHL disease. Case report: We report a case of a female patient of 37 years diagnosed VHL and intervened on several occasions by cerebral hemangioblastoma and renal carcinomas. During its follow-up she was diagnosed 2 gastrinomas functioning under 2 cm were enucleated. Later developed new PNET and underwent a total duodenopancreatectomy without pyloric preservation. Discussion: The management of PNET in VHL is difficult due to the association of multiple tumors in different organs and the morbidity and mortality associated with the surgery of the pancreas. Management must be individualized for each patient, based on the ability to produce hormones and present symptoms, the size and location, and in the context of other tumors that usually present in these patients.
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References
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Citation tools
Sala Hernández Á, Montalvá Orón E, Pareja Ibars E, Ballester Pla N, López Andújar R. Management of pancreatic gastrinoma associated with Von Hippel-Lindau disease: a case report . 4224/2016


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Publication history

Received: 25/01/2016

Accepted: 25/02/2016

Online First: 08/04/2016

Published: 31/01/2017

Article revision time: 27 days

Article Online First time: 74 days

Article editing time: 372 days


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