Year 2023 / Volume 115 / Number 5
Digestive Diseases Image
Metastatic lesion of a choroidal melanoma located in the head of pancreas

261-263

DOI: 10.17235/reed.2022.8843/2022

Javier Castro Rodríguez, Julio Osuna Soto, Emilia Victoria Perdices López,

Abstract
Metastases in pancreas are uncommon, ranging from 2 to 5 % of pancreatic malignancies. Choroidal melanoma is rare, and less than 1% spread to the pancreas. It can cause obstructive jaundice if it affects the pancreatic head region. Advanced disease is associated with poor prognosis, however immunotherapy with PD-1 inhibitors (nivolumab or pembrolizumab), alone or in combination with anti-CTLA-4 antibodies (ipilimumab), has shown an increase in survival.
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References
1. Nakamura Y, Yamada R, Kaneko M, et al. Isolated pancreatic metastasis from malignant melanoma: a case report and literature review. Clinical Journal of Gastroenterology 2019; 12:626–636.
2. Majem M, Manzano JL, Marquez-Rodas I, et al. SEOM clinical guideline for the management of cutaneous melanoma (2020). Clinical and Translational Oncology 2021 May;23(5):948-960.
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Castro Rodríguez J, Osuna Soto J, Perdices López E. Metastatic lesion of a choroidal melanoma located in the head of pancreas. 8843/2022


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Publication history

Received: 07/04/2022

Accepted: 12/04/2022

Online First: 12/05/2022

Published: 05/05/2023

Article Online First time: 35 days

Article editing time: 393 days


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