Year 2019 / Volume 111 / Number 3
Case Report
Endoscopic full-thickness resection (EFTR) after neoadjuvant chemotherapy: is it feasible?

245-247

DOI: 10.17235/reed.2019.5905/2018

Miguel Fraile López, Rodrigo Ugalde Herrá, Fernando Fernández Cadenas,

Abstract
Endoscopic full-thickness resection (EFTR) is a new technique for the resection of colonic lesions with limitations for other techniques such as endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD) due to fibrosis, the location of the lesion or invasion depth. In addition, techniques such as ESD require a long learning curve and unfortunately they are not fully implemented in Western countries. EFTR has numerous indications, which are expanding daily. The Full-Thickness Resection Device® (FTRD) is a promising tool, although it has many limitations and is associated with some risks. One of the main limitations of this resection device is the size of the lesion and it is not recommended for the resection of lesions > 30 mm. Furthermore, tumor size is directly related to the “en bloc” resection rate. On the one hand, this case report suggests that neoadjuvant chemotherapy can modify the lesion size and larger lesions become candidates for EFTR in a second attempt. On the other hand, the concomitant use of systemic anticancer therapy could be a contraindication for the use of FTRD® as it may be associated with late perforations. It is necessary to establish the time between the use of chemotherapy and the use of FTRD® in order to avoid complications. These considerations must be analyzed in future prospective studies.
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References
Aepli P, Criblez D, Baumeler S, Borovicka J, Frei R. Endoscopic full thickness resection (EFTR) of colorectal neoplasms with the Full Thickness Resection Device (FTRD): Clinical experience from two tertiary referral centers in Switzerland. United European Gastroenterol J.2018;6(3):463-70
Schmidt A, Bauerfeind P, Gubler C, Damm M, Bauder M, Caca K. Endoscopic full-thickness resection in the colorectum with a novel over-the-scope device: first experience. Endoscopy. 2015;47(8):719-25
Andrisani G, Pizzicannella M, Martino M, et al. Endoscopic full-thickness resection of superficial colorectal neoplasms using a new over-the-scope clip system: A single-centre study. Dig Liver Dis. 2017;49(9):1009-13.
Meier B, Caca K, Schmidt A. Hybrid endoscopic mucosal resection and full-thickness resection: a new approach for resection of large non-lifting colorectal adenomas (with video). Surg Endosc. 2017;31(10):4268-74.
Valli PV, Mertens J, Bauerfeind P. Safe and successful resection of difficult GI lesions using a novel single-step full-thickness resection device (FTRD®). Surg Endosc. 2018;32(1):289-99.
Schmidt A, Beyna T, Schumacher B, Meining A, Richter-Schrag H-J, Messmann H, et al. Colonoscopic full-thickness resection using an over-the-scope device: a prospective multicentre study in various indications. Gut. 2018;67(7):1280-9.
Marín-Gabriel JC, Díaz-Tasende J, Rodríguez-Muñoz S, Del Pozo-García AJ, Ibarrola-Andrés C. Colonic endoscopic full-thickness resection (EFTR) with the over-the-scope device (FTRD): a short case series. Rev Esp Enferm Dig. 2017;109(3):230-3
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Fraile López M, Ugalde Herrá R, Fernández Cadenas F. Endoscopic full-thickness resection (EFTR) after neoadjuvant chemotherapy: is it feasible? . 5905/2018


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Publication history

Received: 04/09/2018

Accepted: 06/11/2018

Online First: 11/02/2019

Published: 04/03/2019

Article Online First time: 160 days

Article editing time: 181 days


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