Year 2022 / Volume 114 / Number 11
Letter
Ectopic ACTH syndrome in a patient with Crohn’s disease

690-691

DOI: 10.17235/reed.2022.8825/2022

Alberto Pérez Ramírez, Antonio Moreno Loro, Javier Mohigefer Barrera, José Manuel Herrera Justiniano,

Abstract
We present the case of a 62-year-old man with Crohn's disease who consulted for abdominal pain and lower limbs edema. The patient developed Cushing's syndrome due to ectopic secretion of ACTH. Diagnostic imaging tests showed multiple metastatic liver lesions and asymmetric thickening of the ileum, that was suspected as the primary tumor. This tumor produced destabilizing gastrointestinal bleeding and an urgent surgical resection was performed. The histopathological study of the resection specimen confirmed a grade 3 neuroendocrine tumor.
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References
1.Pellino G, Marcellinaro R, Candilio G, De Fatico GS, Guadagno E, Campione S, Santangelo G, Reginelli A, Sciaudone G, Riegler G, Canonico S, Selvaggi F. The experience of a referral centre and literature overview of GIST and carcinoid tumours in inflammatory bowel diseases. Int J Surg. 2016 Apr;28 Suppl 1:S133-41. doi: 10.1016/j.ijsu.2015.12.051. Epub 2015 Dec 18. PMID: 26708852.
2. Pavel M, Öberg K, Falconi M, Krenning EP, Sundin A, Perren A, Berruti A; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org. Gastroenteropancreatic neuroendocrine neoplasms: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2020 Jul;31(7):844-860. doi: 10.1016/j.annonc.2020.03.304. Epub 2020 Apr 6. PMID: 32272208.
3. Mineur L, Boustany R, Vazquez L. Paraneoplastic Cushing Syndrome in Gastrointestinal Neuroendocrine Tumour. Case Rep Oncol. 2021 Sep 23;14(3):1407-1413. doi: 10.1159/000518316. PMID: 34720949; PMCID: PMC8525292.
4. Eriksson B, Klöppel G, Krenning E, Ahlman H, Plöckinger U, Wiedenmann B, et al. Consensus guidelines for the management of patients with digestive neuroendocrine tumors well-differentiated jejunal-ileal tumor/carcinoma. Neuroendocrinol. 2008;87((1)):8–19.
5. Shah CP, Mramba LK, Bishnoi R, Unnikrishnan A, Duff JM, Chandana SR, et al. Survival trends of metastatic small intestinal neuroendocrine tumor: a population-based analysid of SEER database. J Gastrointest Oncol. 2019;10((5)):869–77.
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Pérez Ramírez A, Moreno Loro A, Mohigefer Barrera J, Herrera Justiniano J. Ectopic ACTH syndrome in a patient with Crohn’s disease. 8825/2022


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Publication history

Received: 29/03/2022

Accepted: 05/04/2022

Online First: 12/05/2022

Published: 07/11/2022

Article Online First time: 44 days

Article editing time: 223 days


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