Year 2023 / Volume 115 / Number 2
Letter
Neuroendocrine tumor of the ampulla of Vater. Review of the literature

99

DOI: 10.17235/reed.2022.8981/2022

Miguel Ruiz Moreno, María Ángeles Nieto Vitoria, María Gómez Lozano, Blanca Gallego Pérez, Carmen María Marín Bernabé, Nuria Martínez Sanz, Juan José Martínez Crespo,

Abstract
Neuroendocrine tumors (NETs) or carcinoids represent a small percentage of gastrointestinal neoplasms (2%). The ileum (41.8%), rectum (27.4%) and stomach (8.7%) are the most common locations. We present an unusual case of NET due to its origin in the ampulla of Vater, as an extremely rare cause of biliary obstruction. A bibliographic review of the current recommendations of management and treatment for this case, different from other locations of the gastrointestinal tract is carried out. The curative treatment of choice for early-stage Vater ampulla NETs is Whipple surgery with lymphadenectomy due to Its high rate of lymphatic and metastatic dissemination, regardless of size and histological grade, although there are no updated official guidelines.
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04/09/2023 9:55:36
if the NET of ampulla is less than 3cm, I suggest to perform hot snare by endoscopy to remove the lesion directly, it's safe procedure, I have performed one case with NET of Vater ampulla by endoscopy.


References
Zúñiga Monge D. Tumores neuroendocrinos gastrointestinales. Med Leg Costa Rica. 2013;30(1):89–98.
Bergsland EK, Woltering EA, Rindi G, O’Dorisio TM, Schilsky RL, Liu EH, et al. Neuroendocrine Tumors of the Duodenum and Ampulla of Vater. AJCC Cancer Staging Man. 2017;361–73. doi:10.1007/978-3-319-40618-3_30
Carter JT, Grenert JP, Rubenstein L, Stewart L, Way LW. Neuroendocrine tumors of the ampulla of Vater: biological behavior and surgical management. Arch Surg. 2009 Jun;144(6):527–31.
Kleinschmidt TK, Christein J. Neuroendocrine carcinoma of the ampulla of Vater: a case report, review and recommendations. J Surg Case Reports. 2020;2020(6):1–3. doi: 10.1093/jscr/rjaa119
Yang K, Yun SP, Kim S, Shin N, Park DY, Seo H Il. Clinicopathological features and surgical outcomes of neuroendocrine tumors of ampulla of Vater. BMC Gastroenterol. 2017 May;17(1):70.
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Citation tools
Ruiz Moreno M, Nieto Vitoria M, Gómez Lozano M, Gallego Pérez B, Marín Bernabé C, Martínez Sanz N, et all. Neuroendocrine tumor of the ampulla of Vater. Review of the literature. 8981/2022


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Publication history

Received: 01/06/2022

Accepted: 06/06/2022

Online First: 24/06/2022

Published: 07/02/2023

Article Online First time: 23 days

Article editing time: 251 days


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