Year 2021 / Volume 113 / Number 11
Letter
Lenvatinib in severe hypoglycemia associated with hepatocellular carcinoma

799

DOI: 10.17235/reed.2021.8016/2021

Katherine Milagros Gómez Torres, Carmen Molina Villalba, Matías Estévez Escobar,

Abstract
We present the case of a 24-year-old male with multicentric hepatocellular carcinoma (HCC) over HBV-related compensated liver cirrhosis, on treatment with sorafenib and tenofovir. He had multiple admissions in recent months for severe hypoglycemia episodes with neurological symptoms.
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References
1. Bodnar TW, Acevedo MJ, Pietropaolo M. Management of non-islet-cell tumor hypoglycemia: a clinical review. J Clin Endocrinol Metab 2014;99(3):713-22. DOI: 10.1210/jc.2013-3382
2. Yu B, Douli R, Suarez JA, et al. Non-islet cell tumor hypoglycemia as an initial presentation of hepatocellular carcinoma coupled with end-stage liver cirrhosis: A case report and review of literature. World J Hepatol 2020;12(8):519-24. DOI: 10.4254/wjh.v12.i8.519
3. Garla V, Sonani H, Palabindala V, et al. Non-islet Cell Hypoglycemia: Case Series and Review of the Literature. Front Endocrinol (Lausanne) 2019;10:316. DOI: 10.3389/fendo.2019.00316
4. Izutsu T, Ito H, Fukuda I, et al. Early improvement of Non-islet Cell Tumor Hypoglycemia by chemotherapy using lenvatinib in a case with type 2 diabetes and hepatocellular carcinoma producing big IGF-II. Intern Med 60(9):1427-32. DOI: 10.2169/internalmedicine.5328-20
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Gómez Torres K, Molina Villalba C, Estévez Escobar M. Lenvatinib in severe hypoglycemia associated with hepatocellular carcinoma. 8016/2021


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Publication history

Received: 02/04/2021

Accepted: 16/04/2021

Online First: 05/05/2021

Published: 05/11/2021

Article Online First time: 33 days

Article editing time: 217 days


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