Year 2021 / Volume 113 / Number 7
Letter
Hepatic reactive lymphoid hyperplasia: a difficult differential diagnosis with hepatocarcinoma

552

DOI: 10.17235/reed.2020.7462/2020

Rocío Avellana Moreno, Sofía De la Serna Esteban, Alejandra García-Botella,

Abstract
Hepatic reactive lymphoid hyperplasia (HRLH) is an uncommon lesion. We present the case of a 58-year-old patient with a liver nodule incidentally found by abdominal ultrasonography (US). Liver function, tumor markers, viral serology and immunology were normal. Magnetic resonance imaging (MRI) showed a 16 mm nodule in segment VI-VII, with hypervascular enhancement in the arterial phase, wash-out in late phases, without contrast-retention in the hepatobiliary phase and restriction on diffusion-weighted imaging, suggestive of hepatocellular carcinoma (HCC).
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References
Park HS, Jang KY, Kim YK, et al. Histiocyte-rich reactive lymphoid Hyperplasia of the Liver: Unusual Morphologic Features. J Korean Med Sci. 2008;23(1):156-160.
Zen Y, Fujii T, Nakanuma Y. Hepatic pseudolymphoma: a clinicopathological study of five cases and review of the literature. Mod Pathol. 2010;23(2):244-50.
Sonomura T, Anami S, Takeuchi T, et al. Reactive lymphoid hyperplasia of the liver: Perinodular enhancement on contrast-enhanced computed tomography and magnetic resonance imaging. World J Gastroenterol. 2015; 21(21): 6759-6763.
Dong CH, Lu Q, Wang WP, et al. Contrast-Enhanced Ultrasound Features of Hepatic Reactive Lymphoid Hyperplasia: Correlation With Histopathologic Findings. J Ultrasound Med. 2019; 9999:1–10.
Sato S, Masuda T, Oikawa H, et al. Primary hepatic lymphoma associated with primary biliary cirrhosis. Am J Gastroenterol. 1999;94(6):1669-73.
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Avellana Moreno R, De la Serna Esteban S, García-Botella A. Hepatic reactive lymphoid hyperplasia: a difficult differential diagnosis with hepatocarcinoma. 7462/2020


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Publication history

Received: 08/08/2020

Accepted: 11/09/2020

Online First: 01/12/2020

Published: 07/07/2021

Article revision time: 9 days

Article Online First time: 115 days

Article editing time: 333 days


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