Year 2022 / Volume 114 / Number 7
Letter
Cytomegalovirus colitis seems to be colon cancer. HIV debut

435-436

DOI: 10.17235/reed.2022.8699/2022

María De Armas Conde, Moisés Hernández Barroso, Ana Soto Sánchez, Luis Eduardo Pérez Sánchez, Guillermo Hernández Hernández, Nélida Díaz Jiménez, Manuel Ángel Barrera Gómez,

Abstract
Cytomegalovirus (CMV) infection is very common in immunosuppressed patients. It can y puede afectar a todo el tracto gastrointestinal, presentándose como úlceras o pseudotumores. A 43-year-old male with no personal background of interest, was studied due to constitutional syndrome. The diagnosis was neoplasia of the right colon, reported by colonoscopy and CT scan. A right hemicolectomy was performed with oncologic character. The definitive histology was CMV infectious colitis with positive immunohistochemical staining. Treatment with ganciclovir was started and the patient was diagnosed with HIV infection. The unusual finding of CMV infection as a pseudotumor can simulate, clinically and radiologically, a colonic neoplasm. It has been described in the literature in patients immunocompromised by HIV; however, the absence of risk factors means that it can be confused with a primary neoformative process.
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References
1. Yerushalmy-Feler A, Padlipsky J, Cohen S. Diagnosis and Management of CMV Colitis. Curr Infect Dis Rep. 2019 Feb 15;21(2):5.
2. Yokoyama Y, Yamakawa T, Hirano T, et al. Current Diagnostic and Therapeutic Approaches to Cytomegalovirus Infections in Ulcerative Colitis Patients Based on Clinical and Basic Research Data. Int J Mol Sci. 2020 Mar 31;21(7):2438.
3. Espina Cadena S, Del Valle Sanchez E, Martínez Santos Y, et al. Cytomegalovirus associated rectal ulcer as manifestation of primary HIV infection. Rev Esp Enferm Dig. 2022 Jan 24.
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Citation tools
De Armas Conde M, Hernández Barroso M, Soto Sánchez A, Pérez Sánchez L, Hernández Hernández G, Díaz Jiménez N, et all. Cytomegalovirus colitis seems to be colon cancer. HIV debut. 8699/2022


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Publication history

Received: 07/02/2022

Accepted: 12/02/2022

Online First: 21/02/2022

Published: 07/07/2022

Article Online First time: 14 days

Article editing time: 150 days


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