Year 2021 / Volume 113 / Number 5
Letter
Ribavirin monotherapy for the treatment of chronic hepatitis E in an immunosuppressed patient

386-387

DOI: 10.17235/reed.2020.7266/2020

Katherine Milagros Gómez Torres, Matías Estévez Escobar, Ana Belén Lozano Serrano,

Abstract
We herein report the case of a 54-year-old male patient with a human immunodeficiency virus 1 (HIV-1) infection, usually with low viral loads and CD4 cells < 200-100/mm3 due to thymic exhaustion. He was referred to our clinic because of hypertransaminasemia and cholestasis of a duration of 58 months and liver cirrhosis on FibroScan® without esophageal varices. Nonspecific manifestations included weight loss. Liver disease stigmata and generalized amyotrophy were also present.
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References
1.- Rivero-Juarez A, Lopez-Lopez P, Frias M et al. Hepatitis E Infection in HIV-Infected Patients. Frontiers in Microbiology. 2019;10:1425. DOI:10.3389/fmicb.2019.01425
2.- Dalton HR, Kamar N, Baylis SA et al. EASL Clinical Practice Guidelines on hepatitis E virus infection. Journal of Hepatology. 2018;68(6):1256-1271. DOI:10.1016/j.jhep.2018.03.005
3.- Jagjit Singh GK, Ijaz S, Rockwood N, et al. Chronic Hepatitis E as a cause for cryptogenic cirrhosis in HIV. The Journal of Infection. 2013;66(1):103–106. DOI:10.1016/j.jinf.2011.11.027
4.- Neukam K, Barreiro P, Macías J, et al. Chronic hepatitis E in HIV patients: rapid progression to cirrhosis and response to oral ribavirin. Clinical Infectious Diseases. 2013;57(3):465–468. DOI:10.1093/cid/cit224
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Gómez Torres K, Estévez Escobar M, Lozano Serrano A. Ribavirin monotherapy for the treatment of chronic hepatitis E in an immunosuppressed patient. 7266/2020


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Publication history

Received: 14/05/2020

Accepted: 24/06/2020

Online First: 23/11/2020

Published: 10/05/2021

Article revision time: 34 days

Article Online First time: 193 days

Article editing time: 361 days


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