Year 2024 / Volume 116 / Number 10
Letter
Intestinal perforation caused by Epstein-Barr virus-positive primary diffuse large B-cell lymphoma in a patient with human immunodeficiency virus

581-582

DOI: 10.17235/reed.2023.10124/2023

Qiuli Liu, Qun Bao, Bin Zhao, Kaidong Chen, Xiaojian Weng,

Abstract
We report the case of a 48-year-old male who presented with right lower abdominal pain and a mass for 2 weeks and got constipation for 5 days. An abdominal CT scan conducted before admission at other hospitals revealed an obstruction in the blind ascending colon, which was suspected to be a malignant tumor. Proctoscopy revealed peritoneal implantation metastasis and multiple pelvic lymph nodes. Physical examination was unremarkable except for multiple lymph node enlargements in the inguinal area, without pain. A whole-body contrast-enhanced FDG-PET/CT revealed lymphoma involvement in the ascending colon, peritoneum, bone marrow, and lymph nodes in multiple regions of the body, with DLBCL as a suspected diagnosis. Pathological findings from the colonoscopy revealed atypical lymphocyte infiltration and Immunostaining indicated the presence of atypical lymphocytes with Ki-67 (90%) and tested positive for CD20, CD19, CD10, and BCL-6. Based on the above findings, stage IV DLBCL was diagnosed. Furthermore, EBV-DNA amplification was positive. The patient received R-CHOP treatment for 2 days before experiencing symptoms of fevers, chills, and abdominal pain. He underwent emergency surgery due to intestinal perforation, and preoperative blood tests revealed HIV-positive. The prognosis for the patient is poor due to sepsis.
Share Button
New comment
Comments
No comments for this article
Related articles

Letter

Primary esophageal diffuse large B-cell lymphoma

DOI: 10.17235/reed.2022.9298/2022

Letter

Cytomegalovirus colitis seems to be colon cancer. HIV debut

DOI: 10.17235/reed.2022.8699/2022

Letter

EBVMCU in a liver-transplant patient

DOI: 10.17235/reed.2021.8064/2021

Original

Closure of colonic deep mural injury and perforation with endoclips

DOI: 10.17235/reed.2020.6880/2020

Letter

Secondary gastric lymphoma - Do we know its endoscopic findings?

DOI: 10.17235/reed.2020.6868/2020

Letter to the Editor

Idiopathic esophageal ulcer as an initial manifestation of HIV infection

DOI: 10.17235/reed.2017.5135/2017

Case Report

Jejunal pseudodiverticulosis. Three cases report

DOI: 10.17235/reed.2017.4403/2016

Case Report

Colonic leishmaniasis in a patient with HIV: a case report

DOI: 10.17235/reed.2016.4038/2015

Citation tools
Liu Q, Bao Q, Zhao B, Chen K, Weng X. Intestinal perforation caused by Epstein-Barr virus-positive primary diffuse large B-cell lymphoma in a patient with human immunodeficiency virus. 10124/2023


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 202 visits.
This article has been downloaded 5 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 28/11/2023

Accepted: 04/12/2023

Online First: 14/12/2023

Published: 09/10/2024

Article Online First time: 16 days

Article editing time: 316 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology