Year 2022 / Volume 114 / Number 8
Letter
Sigmoid colon Schwannoma simulating colon cancer

499-500

DOI: 10.17235/reed.2022.8684/2022

María de Armas Conde, Ana Soto Sánchez, Moisés Hernández Barroso, Nélida Díaz Jiménez, Luis Eduardo Pérez Sánchez, Guillermo Hernández Hernández, Manuel Ángel Barrera Gómez,

Abstract
Schwannomas tumours are uncommonly developed in the gastrointestinal tract (2-6%), located in 12% of cases in small and large intestines. An 87-year-old woman was studied due to epigastric pain and dyspepsia. CT scan and colonoscopy showed a neoplastic process in the sigmoid colon. It was performed an oncologic laparoscopic sigmoidectomy. Histological study described a schwannoma and a positive immunohistochemistry to S-100. The diagnostic challenge is that this is a submucosa lesion, therefore, endoscopy biopsy is realized only in the mucosa. This becomes the differential diagnostic very difficult in order to differentiate from another mesenchymal tumor (GIST or leiomyoma). The immunohistochemistry helps in the diagnostic if it is positive to S- 100 and negative to C-KIT, CD-34, actine and desmine (findings of GIST tumors and leiomyoma). In conclusion, schwannoma diagnostic is tough. Those are asymptomatic tumors with nonspecific radiological findings. Diagnostic confirmation is a S-100 positive immunohistochemistry in the histological study.
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References
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de Armas Conde M, Soto Sánchez A, Hernández Barroso M, Díaz Jiménez N, Pérez Sánchez L, Hernández Hernández G, et all. Sigmoid colon Schwannoma simulating colon cancer. 8684/2022


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Publication history

Received: 05/02/2022

Accepted: 20/02/2022

Online First: 14/03/2022

Published: 27/07/2022

Article revision time: 12 days

Article Online First time: 37 days

Article editing time: 172 days


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