Year 2023 / Volume 115 / Number 1
Letter
Inflammatory myofibroblastic tumor presenting as a subepithelial lesion of the colon

44-45

DOI: 10.17235/reed.2022.8968/2022

Mariana Coelho, Cristiana Sequeira, João Cruz, Ricardo Freire, Élia Gamito, Ana Paula Oliveira,

Abstract
We present the case of a 42-year-old male admitted to the emergency department for a 15-day history of diarrhea, with bloody stools in the past 7 days. The patient denied abdominal pain or distension as well as any constitutional symptoms. On physical examination he presented good general health condition, with abdomen slightly tender in the lower quadrants; digital rectal examination was remarkable for the presence of dark blood. Laboratory evaluation revealed new onset normocytic anemia (Hb 10.8 g/dL, MCV 89 fL) and RCP of 3.3 mg/dL. Colonoscopy was performed, which showed a large cecal subepithelial lesion, with surface ulcerations. Histology reported mixed inflammatory infiltrate but no malignancy. Further investigation was carried out with an abdominal and pelvic computerized tomography that, other than the cecal mass, showed multiple infracentimetric mesenteric lymph nodes. A right laparoscopic hemicolectomy was performed. Pathological analysis led to the unusual diagnosis of inflammatory myofibroblastic tumor (IMT) of the colon. There was no sign of recurrence after 6 months of follow-up.
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References
Spyrou I, Davakis S, Moris D, et al. Inflammatory pseudotumour of the colon. Ann R Coll Surg Engl. 2017;99(5):e151-e153. doi:10.1308/rcsann.2017.0064
Wang Y, Zhuang Y, Pan Y. Colonic Inflammatory Myofibroblastic Tumor. J Gastrointest Surg. 2021;25(3):854-855. doi:10.1007/s11605-020-04711-6
Gleason BC, Hornick JL. Inflammatory myofibroblastic tumours: where are we now?. J Clin Pathol. 2008;61(4):428-437. doi:10.1136/jcp.2007.049387
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Coelho M, Sequeira C, Cruz J, Freire R, Gamito É, Oliveira A, et all. Inflammatory myofibroblastic tumor presenting as a subepithelial lesion of the colon. 8968/2022


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Publication history

Received: 28/05/2022

Accepted: 31/05/2022

Online First: 03/06/2022

Published: 12/01/2023

Article Online First time: 6 days

Article editing time: 229 days


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