Year 2023 / Volume 115 / Number 11
Letter
Severe outbreak of ulcerative colitis and cerebral neoplasia. Difficult management in COVID time

657

DOI: 10.17235/reed.2023.9527/2023

Samer Mouhtar El Hálabi, Teresa Valdés Delgado, Belén Maldonado Pérez, María Belvis Jiménez, Federico Argüelles Arias,

Abstract
A 61-year-old male diabetic patient, diagnosed with ulcerative colitis (UC) 30 years ago, currently under treatment with mesalazine is presented. He was admitted to the emergency department due to a severe outbreak of UC, with 15 depositions daily, rectal bleeding and poor general condition. A brain CT-scan was carried out in the emergency department due to a sudden self-limited aphasia. A left frontal lesion of 45x38 mms with a prominent perilesional edema and with a displacement of the midline was reported. This was believed to be a meningioma (figure 1A). Urgent neurosurgery was not performed, prioritizing the severe flare-up UC. Based on this, full-dose metilprednisolone was administered.
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References
1. Sicilia B, García-López S, González-Lama, et al. Guía GETECCU 2020 para el tratamiento de la colitis ulcerosa. Gastroenterol Hepatol. 2020;43(Supl 1):1-57.
2. Bonovas S, Fiorino G, Allocca M, et al. Biologic Therapies and Risk of Infection and Malignancy in Patients with Inflammatory Bowel Disease: A Systematic Review and Network Meta-analysis. Clin Gastroenterol Hepatol. 2016 Oct;14(10):1385-1397
3. Chaparro M, Ramas M, Benítez JM, et al. Extracolonic cancer in inflammatory bowel disease. Data from the GETECCU Eneida Registry. Am J Gastroenterol. 2017; 112: 1135-43.
4. Nalatagla N, Falloon K, Tran G, et al. Effect of Accelerated infliximab induction on short- and longterm outcomes of acute severe ulcerative colitis: A retrospective multi-center study meta-analysis. Clin Gastroenterol Hepatol. 2019 February ; 17(3): 502–509.
5. Zara Izadi, et al. Association Between Tumor Necrosis Factor Inhibitors and the Risk of Hospitalization or Death Among Patients With Immune-Mediated Inflammatory Disease and COVID-19. JAMA Network Open. 2021;4(10):e2129639
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Citation tools
Mouhtar El Hálabi S, Valdés Delgado T, Maldonado Pérez B, Belvis Jiménez M, Argüelles Arias F. Severe outbreak of ulcerative colitis and cerebral neoplasia. Difficult management in COVID time. 9527/2023


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Publication history

Received: 13/02/2023

Accepted: 21/02/2023

Online First: 17/03/2023

Published: 13/11/2023

Article Online First time: 32 days

Article editing time: 273 days


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