Year 2017 / Volume 109 / Number 9
Letter to the Editor
Fecal transplantation as a treatment for Clostridium difficile infection in patients with ulcerative colitis

670

DOI: 10.17235/reed.2017.4941/2017

Marta Izquierdo Romero, Pilar Varela Trastoy, Alejo Mancebo Mata,

Abstract
Clostridium difficile (CD) infection is currently the most frequent etiology of nosocomial diarrhea. Besides, its incidence is progressively increasing in ambulatory patients. Inflammatory bowel disease (IBD) is a risk factor of CD infection itself, but also due to the regular immunosuppressive treatment used in these patients. At the present time, fecal transplantation (FT) is a safe and cost-effective alternative if the previous antibiotic treatments have failed. Similar outcomes between patients with IBD and general population have been reported. We present a case of a patient with ulcerative colitis and recurrent CD infection successfully treated with FT.
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References
Fischer M, Kao D, Kelly C, Kuchipudi A, Jafri S, Blumenkehl M, et al. Fecal Microbiota Transplantation is Safe and Efficacious for Recurrent or Refractory Clostridium difficile Infection in Patients with Inflammatory Bowel Disease. Inflamm Bowel Dis. 2016; 22: 2402-2409.
DOI: 10.1097/MIB.0000000000000908
Di Bella S, Gouliouris T and Petrosillo N. Fecal microbiota transplantation (FMT) for Clostridium difficile infection: Focus on immunocompromised patients. J Infect Chemother. 2015; 21: 230-237.
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Leffler D and Lamont J. Clostridium difficile Infection. N Engl J Med. 2015; 372: 1539-1548.
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Ramos Martínez A, Ortiz Balbuena J, Curto García I, Asensio Vegas A, Martínez Ruiz R, Múñez Rubio E, et al. Factores de riesgo de diarrea por Clostridium difficile en pacientes con enfermedad inflamatoria intestinal. Rev Esp Enferm Dig. 2015; 107(1): 4-9.
Ponte A, Pinho R, Mota M, Silva J, Vieira N, Oliveira R, et al. Initial experience with fecal microbiota transplantation in Clostridium difficile infection – transplant protocol and preliminary results. Rev Esp Enferm Dig. 2015; 107(7): 402-407.
DOI: 10.17235/reed.2015.3767/2015
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Izquierdo Romero M, Varela Trastoy P, Mancebo Mata A. Fecal transplantation as a treatment for Clostridium difficile infection in patients with ulcerative colitis. 4941/2017


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Publication history

Received: 08/03/2017

Accepted: 22/03/2017

Online First: 27/07/2017

Published: 31/08/2017

Article Online First time: 141 days

Article editing time: 176 days


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The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
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