Year 2018 / Volume 110 / Number 5
Original
Fecal microbiota transplantation in refractory or recurrent Clostridium difficile infection: a real-life experience in a non-academic center

311-315

DOI: 10.17235/reed.2018.5099/2017

Ana Ponte, Rolando Pinho, Margarida Mota, Joana Silva, Nuno Vieira, Rosa Oliveira, Jaime Rodrigues, Mafalda Sousa, Isabel Sousa, João Carvalho,

Abstract
Aim: this study aimed to describe the efficacy and safety of fecal microbiota transplantation (FMT) for the treatment of refractory and recurrent Clostridium difficile infection (CDI). Methods: this was an observational study of patients with refractory or recurrent CDI treated with FMT between June 2014 and January 2017. Primary and secondary outcomes were the resolution of diarrhea without CDI recurrence within two months after one or more FMT. A descriptive analysis was performed. Results: thirty-four FMT were performed in 28 patients, 88.2% (n = 30) using an upper route with a gastroscopy and 11.8% (n = 4) with colonoscopy; 50% (n = 17) of FMT were due to recurrent CDI and 50% (n = 17) were due to refractory CDI. The overall cure rate of upper FMT was 87.5% (21/24) and 100% (4/4) when colonoscopy was performed. A cure was achieved after one FMT in 88% (22/25) of cases and after two or more FMT in 8% (2/25) of cases, resulting in an overall cure rate of 96% (24/25). No severe adverse events were reported. Conclusion: FMT constitutes an effective and safe approach for the management of refractory and recurrent CDI, with an overall cure rate of 96% and no reported severe adverse events.
Share Button
New comment
Comments
No comments for this article
References
1) Gupta S, Allen-Vercoe E, Petrof EO. Fecal microbiota transplantation: in perspective. Therap Adv Gastroenterol. 2016 Mar;9(2):229-39.
DOI: 10.1177/1756283X15607414
2) Bakken JS, Borody T, Brandt LJ, et al. Treating Clostridium difficile infection with fecal microbiota transplantation. Clin Gastroenterol Hepatol. 2011 Dec;9(12):1044-9.
3) Brandt LJ, Aroniadis OC, Mellow M, et al. Long-term follow-up of colonoscopic fecal microbiota transplant for recurrent Clostridium difficile infection. Am J Gastroenterol. 2012 Jul;107(7):1079-87.
DOI: 10.1038/ajg.2012.60
4) Brandt LJ, Aroniadis OC. An overview of fecal microbiota transplantation: techniques, indications, and outcomes. Gastrointest Endosc. 2013 Aug;78(2):240-9.
DOI: 10.1016/j.gie.2013.03.1329
5) Rubin TA, Gessert CE, Aas J, et al. Fecal microbiome transplantation for recurrent Clostridium difficile infection: report on a case series. Anaerobe. 2013 Feb;19:22-6.
DOI: 10.1016/j.anaerobe.2012.11.004
6) Choi HH, Cho YS. Fecal Microbiota Transplantation: Current Applications, Effectiveness, and Future Perspectives. Clin Endosc. 2016 May;49(3):257-65.
DOI: 10.5946/ce.2015.117
7) Cammarota G, Ianiro G, Tilg H, et al. European consensus conference on faecal microbiota transplantation in clinical practice. Gut. 2017 Apr;66(4):569-580.
DOI: 10.1136/gutjnl-2017-314049
8) Cammarota G, Ianiro G, Gasbarrini A. Fecal microbiota transplantation for the treatment of Clostridium difficile infection: a systematic review. J Clin Gastroenterol. 2014 Sep;48(8):693-702.
DOI: 10.1097/MCG.0000000000000046
9) Brandt LJ. American Journal of Gastroenterology Lecture: Intestinal microbiota and the role of fecal microbiota transplantation (FMT) in treatment of C. difficile infection. Am J Gastroenterol. 2013 Feb;108(2):177-85.
DOI: 10.1038/ajg.2012.450
10) Kassam Z, Lee CH, Yuan Y, et al. Fecal microbiota transplantation for Clostridium difficile infection: systematic review and meta-analysis. Am J Gastroenterol. 2013 Apr;108(4):500-8.
DOI: 10.1038/ajg.2013.59
11) van Nood E, Vrieze A, Nieuwdorp M, et al. Duodenal infusion of donor feces for recurrent Clostridium difficile. N Engl J Med. 2013 Jan 31;368(5):407-15.
DOI: 10.1056/NEJMoa1205037
12) Postigo R, Kim JH. Colonoscopic versus nasogastric fecal transplantation for the treatment of Clostridium difficile infection: a review and pooled analysis. Infection. 2012 Dec;40(6):643-8.
DOI: 10.1007/s15010-012-0307-9
13) Ponte A, Pinho R, Mota M, et al. Initial experience with fecal microbiota transplantation in Clostridium difficile infection - transplant protocol and preliminary results. Rev Esp Enferm Dig. 2015 Jul;107(7):402-7.
DOI: 10.17235/reed.2015.3767/2015
14) Surawicz CM, Brandt LJ, Binion DG, et al. Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections. Am J Gastroenterol 2013;108(4): 478-98; quiz 499.
DOI: 10.1038/ajg.2013.4
15) Newcombe, Robert G. "Two-Sided Confidence Intervals for the Single Proportion: Comparison of Seven Methods," Statistics in Medicine, 17, 857-872 (1998).
16) Wilson, E. B. "Probable Inference, the Law of Succession, and Statistical Inference," Journal of the American Statistical Association, 22, 209-212 (1927).
17) Li YT, Cai HF, Wang ZH, et al. Systematic review with meta-analysis: long-term outcomes of faecal microbiota transplantation for Clostridium difficile infection. Aliment Pharmacol Ther. 2016 Feb;43(4):445-57.
DOI: 10.1111/apt.13492
18) Borody T, Fischer M, Mitchell S, et al. Fecal microbiota transplantation in gastrointestinal disease: 2015 update and the road ahead. Expert Rev Gastroenterol Hepatol. 2015;9(11):1379-91.
DOI: 10.1586/17474124.2015.1086267
19) Drekonja D, Reich J, Gezahegn S, et al. Fecal microbiota transplantation for clostridium difficile infection: a systematic review. Ann Intern Med 2015; 162: 630–8.
DOI: 10.7326/M14-2693
20) Rossen NG, MacDonald JK, de Vries EM, et al. Fecal microbiota transplantation as novel therapy in gastroenterology: a systematic review. W J Gastroenterol 2015; 21: 5359–71.
DOI: 10.3748/wjg.v21.i17.5359
21) Gough E, Shaikh H, Manges AR. Systematic review of intestinal microbiota transplantation (fecal bacteriotherapy) for recurrent clostridium difficile infection. Clin Infect Dis 2011; 53: 994–1002.
DOI: 10.1093/cid/cir632
22) Debast SB, Bauer MP, Kuijper EJ, et al. European Society of Clinical Microbiology and Infectious Diseases. European Society of Clinical Microbiology and Infectious Diseases: update of the treatment guidance document for Clostridium difficile infection. Infec Dis 2014;20(Suppl 2):1-26.
DOI: 10.1111/1469-0691.12418
23) Smits LP, Bouter KE, de Vos WM, et al. Therapeutic potential of fecal microbiota transplantation. Gastroenterology. 2013 Nov;145(5):946-53.
DOI: 10.1053/j.gastro.2013.08.058
24) Borody TJ, Khoruts A. Fecal microbiota transplantation and emerging applications. Nat Rev Gastroenterol Hepatol. 2011 Dec 20;9(2):88-96.
DOI: 10.1038/nrgastro.2011.244
25) Youngster I, Russell GH, Pindar C, Ziv-Baran T, Sauk J, Hohmann EL. Oral, capsulized, frozen fecal microbiota transplantation for relapsing Clostridium difficile infection. JAMA. 2014 Nov 5;312(17):1772-8.
DOI: 10.1001/jama.2014.13875
Related articles

Letter

Duodenal pseudolipomatosis. Literature review and case report of a very unusual finding

DOI: 10.17235/reed.2024.10673/2024

Review

Advancements in biliopancreatic endoscopy - A comprehensive review of artificial intelligence in EUS and ERCP

DOI: 10.17235/reed.2024.10456/2024

Original

Complications and survival following percutaneous endoscopic gastrostomy tube placement

DOI: 10.17235/reed.2024.10335/2024

Letter

Beyond digestive pathology: endoscopic study in systemic disease

DOI: 10.17235/reed.2024.10324/2024

Special Article

Endoscopic management of pancreatic collections. Endoscopic Ultrasound Group, Spanish Society of Digestive Endoscopy (GSEED-USE) Clinical Guidelines

DOI: 10.17235/reed.2024.10276/2024

Letter

Endoscopic removal of an esophageal foreign body and endoscopic closure of its associated perforation with early mediastinitis

DOI: 10.17235/reed.2024.10182/2023

Letter

Gastric lymphangioma. Diagnosis by endoscopic resection of a foreign entity

DOI: 10.17235/reed.2023.10085/2023

Letter

Hepatic invasion of a gastric ulcer confirmed by endoscopy and surgery

DOI: 10.17235/reed.2023.9999/2023

Letter

Blue rubber bleb nevus syndrome

DOI: 10.17235/reed.2023.9913/2023

Letter

Water pressure method combined with magnifying endoscopy for esophageal endoscopic submucosal dissection

DOI: 10.17235/reed.2023.9828/2023

Letter

Capsule endoscopy diagnosis of gastrointestinal melanoma

DOI: 10.17235/reed.2023.9803/2023

Letter

Small bowel cavernous hemangioma as an uncommon cause of iron-deficiency anemia

DOI: 10.17235/reed.2023.9778/2023

Letter

Forecast models to predict the demand for endoscopic procedures in a tertiary unit: a prospective validation

DOI: 10.17235/reed.2023.9763/2023

Letter

Calcifying fibrous tumor and pathological analysis

DOI: 10.17235/reed.2023.9739/2023

Letter

Gastric mucormycosis presenting as diffuse thickening of the gastric wall with enhancement

DOI: 10.17235/reed.2023.9705/2023

Editorial

Training and competence in Digestive Endoscopy: Statement Position Paper from the Spanish Society of Digestive Diseases

DOI: 10.17235/reed.2023.9692/2023

Letter

Endoscopic observation of a rare duodenal tumor

DOI: 10.17235/reed.2023.9679/2023

Letter

Endoscopic rescue of a fistulizing biliary plastic stent

DOI: 10.17235/reed.2023.9673/2023

Letter

MALT lymphoma of the colon: an endoscopic challenge

DOI: 10.17235/reed.2023.9595/2023

Letter

Pancreatic metastasis of extra-skeletal mesenchymal chondrosarcoma diagnosed by ultrasound endoscopy-guided fine-needle aspiration

DOI: 10.17235/reed.2023.9586/2023

Letter

Closure of a perforated endoscopic submucosal dissection eschar using three over-the-scope clips

DOI: 10.17235/reed.2023.9546/2023

Letter

Direct peroral cholangioscopy with conventional upper gastrointestinal endoscope

DOI: 10.17235/reed.2023.9514/2023

Original

Mortality in patients with unresectable gastric cancer complicated with tumor bleeding

DOI: 10.17235/reed.2023.9508/2023

Letter

Endoscopic endoluminal therapy with the Eso-SPONGE® system for the treatment of spontaneous esophageal perforation with associated paraoesophageal collection

DOI: 10.17235/reed.2023.9490/2023

Letter

Sigmoid volvulus management, only endoscopic devolvulation?

DOI: 10.17235/reed.2023.9488/2023

Letter

Bariatric endoscopy, care-curative medicine and legal conflicts. Spanish Bariatric Endoscopy Group (Gettemo-SEED) Positioning

DOI: 10.17235/reed.2023.9476/2023

Original

Time trends and endoscopic management of foreign body ingestion in the upper GI tract: a retrospective analysis of 1,152 cases in China

DOI: 10.17235/reed.2023.9426/2022

Letter

Isolated Jejunal Crohn's Disease: a challenging diagnosis

DOI: 10.17235/reed.2022.9423/2022

Letter

New technique for the endoscopic removal of long foreign bodies

DOI: 10.17235/reed.2023.9398/2022

Digestive Diseases Image

The role of magnification endoscopy in the early diagnosis of gastric signet ring cell carcinoma

DOI: 10.17235/reed.2023.9364/2022

Digestive Diseases Image

Whipple’s disease – A typical endoscopic finding of a rare disease

DOI: 10.17235/reed.2022.9338/2022

Special Article

Spanish Intragastric Balloon Consensus Statement (SIBC): practical guidelines based on experience of over 20 000 cases

DOI: 10.17235/reed.2022.9322/2022

Letter

Endoscopic ampullectomy of a giant pedunculated ampullary adenoma

DOI: 10.17235/reed.2022.9316/2022

Letter

Endoscopic “purse-string” to close a rectal endoscopic submucosal dissection eschar with intentional muscular sectioning

DOI: 10.17235/reed.2022.9271/2022

Original

Risk factors associated to argon plasma coagulation treatment failure in patients with chronic radiation proctopathy

DOI: 10.17235/reed.2023.9258/2022

Letter

A “push-and-pull” trick for endoscopic removal of buckyballs impacted in the esophagus and gastric fundus

DOI: 10.17235/reed.2022.9222/2022

Letter

A rare case of esophageal anthracosis presenting as a submucosal tumor

DOI: 10.17235/reed.2022.9206/2022

Digestive Diseases Image

A case of esophageal histoplasmosis mimicking carcinoma on endoscopy

DOI: 10.17235/reed.2023.9167/2022

Digestive Diseases Image

A rare endoscopic pattern in a patient with gastroesophageal reflux disease

DOI: 10.17235/reed.2022.9124/2022

Digestive Diseases Image

Esophageal tuberculosis

DOI: 10.17235/reed.2022.9108/2022

Letter

Efficacy-safety profile of the video capsule endoscopy in the study of the small bowel: experience over 100 consecutive procedures

DOI: 10.17235/reed.2022.9102/2022

Original

Predicting the future: introducing business analytics to endoscopy units

DOI: 10.17235/reed.2022.9094/2022

Digestive Diseases Image

Esophagopleural fistula due to empyema necessitans

DOI: 10.17235/reed.2022.9085/2022

Letter

Transparent cap-assisted endoscopic retrieval of a sharp foreign body in the esophagus

DOI: 10.17235/reed.2022.9059/2022

Review

“Out of the box” new therapeutic strategies for Crohn´s disease: moving beyond biologics

DOI: 10.17235/reed.2022.9010/2022

Letter

Iron pill-induced gastritis: an unrecognized side effect of iron-deficiency anemia

DOI: 10.17235/reed.2022.9005/2022

Digestive Diseases Image

Pneumatosis intestinalis: a rare endoscopic feature of colonic ischemia

DOI: 10.17235/reed.2022.8980/2022

Review

Artificial intelligence in gastrointestinal endoscopy — Evolution to a new era

DOI: 10.17235/reed.2022.8961/2022

Letter

Primary intestinal melanoma?

DOI: 10.17235/reed.2022.8944/2022

Letter

Primary small bowel follicular lymphoma: the role of balloon-assisted enteroscopy in diagnosis and follow-up

DOI: 10.17235/reed.2022.8943/2022

Letter

Intestinal amyloidosis: a diagnostic challenge

DOI: 10.17235/reed.2022.8934/2022

Letter

Successful gallstone ileus treatment by endoscopy

DOI: 10.17235/reed.2022.8898/2022

Letter

Endoscopic submucosal dissection for exploration and removal of a gastric buried foreign body

DOI: 10.17235/reed.2022.8885/2022

Letter

Kaposi’s sarcoma with gastric and rectal involvement in HIV patient

DOI: 10.17235/reed.2022.8880/2022

Letter

Esophagomediastinal fistula: a rare case of gastrointestinal tuberculosis

DOI: 10.17235/reed.2022.8875/2022

Original

Predictive value of patency capsule and magnetic resonance enterography for capsule endoscopy retention in patients with established Crohn’s disease

DOI: 10.17235/reed.2022.8848/2022

Original

Half of the patients with subepithelial tumors present borderline or pathologic anxiety-distress and carcinophobia: a multicenter cohort study

DOI: 10.17235/reed.2022.8836/2022

Review

Efficacy and safety of fecal microbiota transplant for recurrent Clostridium difficile infection in inflammatory bowel disease: a systematic review and meta-analysis

DOI: 10.17235/reed.2022.8814/2022

Letter

Digestive tract MALT lymphoma, an unusual location

DOI: 10.17235/reed.2022.8800/2022

Letter

Impact of the SARS-CoV-2 pandemic on pancreatic cancer: diagnosis and short-term survival

DOI: 10.17235/reed.2022.8772/2022

Letter

Esophageal hyperkeratosis as an uncommon manifestation of gastroesophageal reflux disease

DOI: 10.17235/reed.2022.8764/2022

Letter

Endoscopy-negative esophageal foreign body - The role of computed tomography

DOI: 10.17235/reed.2022.8770/2022

Digestive Diseases Image

Esophageal epidermoid metaplasia: an unusual condition

DOI: 10.17235/reed.2022.8708/2022

Letter

Primary intestinal lymphangiectasia: a rare disease as a cause of protein-losing enteropathy

DOI: 10.17235/reed.2022.8673/2022

Letter

Clinical and endoscopic findings in gastrointestinal amyloidosis: a single-center experience

DOI: 10.17235/reed.2022.8656/2022

Digestive Diseases Image

Ileal neuroendocrine tumor as an uncommon cause of obscure gastrointestinal bleeding

DOI: 10.17235/reed.2022.8641/2022

Special Article

Development of a list of minimum procedures for certifying competence in gastrointestinal endoscopy by the Delphi method

DOI: 10.17235/reed.2022.8553/2021

Original

Esophageal fish bone impaction: the importance of early diagnosis and treatment to avoid severe complications

DOI: 10.17235/reed.2022.8537/2021

Letter

Emergency endoscopy in pediatrics during the SARS-CoV-2 pandemic in a tertiary center – A changing pattern?

DOI: 10.17235/reed.2021.8532/2021

Letter

Early work activities after sedation with propofol in digestive endoscopy. Reply

DOI: 10.17235/reed.2021.8478/2021

Letter

An unexpected location for a metastasis from esophageal squamous carcinoma

DOI: 10.17235/reed.2021.8467/2021

Digestive Diseases Image

Multiple bezoars causing small bowel obstruction: a unique case of resolution with upper and low GI endoscopy

DOI: 10.17235/reed.2021.8459/2021

Original

Outcomes of peroral endoscopic myotomy in patients with spastic esophageal motility disorders that do not fulfill Chicago Classification criteria

DOI: 10.17235/reed.2022.8455/2021

Original

A new biodegradable stent in bilio-pancreatic diseases: a prospective multi-center feasibility study

DOI: 10.17235/reed.2022.8451/2021

Letter

Symptom resolution of bile reflux gastritis after transoral gastric outlet reduction in a patient with Billroth II anastomosis

DOI: 10.17235/reed.2021.8406/2021

Letter

Upper gastrointestinal bleeding due to duodenum diverticulum: a challenge for the endoscopist

DOI: 10.17235/reed.2021.8373/2021

Original

The role of endoscopic submucosal dissection in the management of gastric inflammatory fibroid polyps: a single-center experience

DOI: 10.17235/reed.2021.8347/2021

Original

Safety of endoscopist-administered deep sedation with propofol in ASA III patients

DOI: 10.17235/reed.2021.8289/2021

Letter

Strange coincidence in the gut: pseudomelanosis duodeni diagnosed by capsule endoscopy and active bleeding due to angiodysplasia

DOI: 10.17235/reed.2021.8254/2021

Digestive Diseases Image

A case of duodenal-type follicular lymphoma

DOI: 10.17235/reed.2021.8233/2021

Digestive Diseases Image

Endoscopic resection of a duodenal neuroendocrine tumor

DOI: 10.17235/reed.2021.8232/2021

Letter

What are the odds? Duodenum adenocarcinoma as a primary metachronic neoplasia

DOI: 10.17235/reed.2021.8200/2021

Digestive Diseases Image

Duodenal-type follicular lymphoma: a silent tumor

DOI: 10.17235/reed.2021.8149/2021

Original

Evaluation of a new composite score combining SPICE and protrusion angle scores to distinguish submucosal lesions from innocent bulges

DOI: 10.17235/reed.2021.8080/2021

Digestive Diseases Image

Primary or idiopathic intestinal pneumatosis: a rare casual endoscopic finding

DOI: 10.17235/reed.2021.8049/2021

Letter

Early work activities after sedation with propofol in digestive endoscopy

DOI: 10.17235/reed.2021.7996/2021

Original

Artificial intelligence and capsule endoscopy: automatic detection of enteric protruding lesions using a convolutional neural network

DOI: 10.17235/reed.2021.7979/2021

Editorial

Cardiorespiratory complications directly related to endoscopy: associated or not with sedation?

DOI: 10.17235/reed.2021.7885/2021

Letter

Duodenal lymphangiectasias — The first sign of pancreatic adenocarcinoma

DOI: 10.17235/reed.2021.7823/2021

Letter

Bochdalek hernia: use of capsule endoscopy

DOI: 10.17235/reed.2021.7760/2020

Letter

Safety in digestive endoscopy during the ongoing COVID-19 pandemic

DOI: 10.17235/reed.2021.7748/2020

Digestive Diseases Image

Endoscopic forceps removal for complicated magnetic beads impaction

DOI: 10.17235/reed.2021.7731/2020

Letter

Importance of assessing for cannabis use prior to propofol sedation for endoscopy

DOI: 10.17235/reed.2020.7716/2020

Original

The diagnostic value of capsule endoscopy in children with intestinal lymphangiectasia

DOI: 10.17235/reed.2021.7682/2020

Original

Capsule enteroscopy versus radionuclide scintigraphy for the diagnosis of obscure gastrointestinal bleeding

DOI: 10.17235/reed.2021.7633/2020

Original

Poor agreement between clinical screening and universal pre-procedure SARS-CoV-2 PCR testing prior to endoscopy

DOI: 10.17235/reed.2021.7612/2020

Original

Management of small intestinal bacterial overgrowth by pediatric gastroenterologists in Spain

DOI: 10.17235/reed.2020.7582/2020

Letter

Endoscopic diagnosis of primary and recurrent mantle cell lymphomas

DOI: 10.17235/reed.2020.7538/2020

Original

Small-bowel transit time in capsule endoscopy: a determinant factor for the diagnosis of small-bowel bleeding

DOI: 10.17235/reed.2021.7487/2020

Letter

Leukocytoclastic vasculitis with cutaneous and systemic (intestinal) involvement. Diagnosis by capsule endoscopy

DOI: 10.17235/reed.2020.7474/2020

Original

Capsule retention caused by cryptogenic multifocal ulcerous stenosing enteritis

DOI: 10.17235/reed.2021.7466/2020

Digestive Diseases Image

Esophageal involvement in a patient with pemphigus vulgaris

DOI: 10.17235/reed.2020.7417/2020

Original

Prospective comparative study of the treatment of Helicobacter pylori with antibiotic susceptibility testing-guided triple therapy compared to quadruple therapy with bismuth-metronidazole-tetracycline subcitrate

DOI: 10.17235/reed.2020.7395/2020

Letter

Basic training in gastrointestinal endoscopy: recording images

DOI: 10.17235/reed.2020.7385/2020

Original

Evaluation of endoscopy requests in the resumption of activity during the SARS-CoV-2 pandemic: denial of nonindicated requests and prioritization of accepted requests

DOI: 10.17235/reed.2020.7375/2020

Original

Obliteration of gastric varices guided by eco-endoscopy with coils insertion coated with expandable hydrogel polymers

DOI: 10.17235/reed.2020.7340/2020

Letter

Primary gastric adenocarcinoma in a patient with Peutz-Jeghers syndrome

DOI: 10.17235/reed.2020.7323/2020

Original

Can we predict an incomplete capsule endoscopy? Results of a multivariate analysis using a logistic regression model

DOI: 10.17235/reed.2021.7320/2020

Digestive Diseases Image

A combined endoscopy and laparoscopic approach for a gastric perforation due to intragastric balloon insertion

DOI: 10.17235/reed.2020.7312/2020

Letter

Concordance between capsule endoscopy and device-assisted enteroscopy in small-bowel lesions

DOI: 10.17235/reed.2020.7295/2020

Letter

Diagnostic yield of the capsule endoscopy and enteroscopy combination for early small bowel carcinoid tumors

DOI: 10.17235/reed.2020.7262/2020

Original

Pan-enteric capsule for bleeding high-risk patients. Can we limit endoscopies?

DOI: 10.17235/reed.2020.7196/2020

Original

The role of endoscopy in caustic ingestion in the pediatric population: experience in a tertiary center

DOI: 10.17235/reed.2020.7171/2020

Original

Fecal microbiota transplantation in the intestinal decolonization of carbapenamase-producing enterobacteriaceae

DOI: 10.17235/reed.2020.7150/2020

Review

COVID-19 and the digestive system: protection and management during the SARS-CoV-2 pandemic

DOI: 10.17235/reed.2020.7128/2020

Special Article

Recommendations by the SEPD and AEG, both in general and on the operation of gastrointestinal endoscopy and gastroenterology units, concerning the current SARS-CoV-2 pandemic (March, 18)

DOI: 10.17235/reed.2020.7052/2020

Special Article

Small bowel enteroscopy – A joint clinical guideline by the Spanish and Portuguese small-bowel study groups

DOI: 10.17235/reed.2020.7020/2020

Review

The diagnostic and predictive value of fecal calprotectin and capsule endoscopy for small-bowel Crohn’s disease: a systematic review and meta-analysis

DOI: 10.17235/reed.2020.6996/2020

Review

Advanced therapy by device-assisted enteroscopy

DOI: 10.17235/reed.2020.6971/2020

Special Article

Main prophylactic measures in bariatric endoscopy. Spanish Expert Recommendations Guideline

DOI: 10.17235/reed.2020.6970/2020

Digestive Diseases Image

Obscure gastrointestinal bleeding in the setting of blue rubber bleb nevus syndrome with extensive small bowel involvement

DOI: 10.17235/reed.2020.6963/2020

Original

Predictors for finding lesions in the small bowel by enteroscopy after a positive capsule endoscopy

DOI: 10.17235/reed.2020.6956/2020

Review

Cardiorespiratory complications of digestive endoscopy not related to sedation

DOI: 10.17235/reed.2020.6917/2020

Letter

Are we experiencing a technological revolution? The novel motorized PowerSpiral enteroscope (PSE): a case of total oral enteroscopy

DOI: 10.17235/reed.2020.6881/2020

Original

Recurrent small-bowel bleeding from a Dieulafoy’s lesion after combined endoscopic treatment

DOI: 10.17235/reed.2020.6899/2020

Letter

Luetic gastritis: an uncommon cause of gastritis

DOI: 10.17235/reed.2020.6870/2020

Letter

A legal issue with dental prostheses and their possible complications

DOI: 10.17235/reed.2020.6864/2020

Original

Index of the Mayo Endoscopy and Ulcerative Colitis Endoscopy Index of Severity: are they equally valid?

DOI: 10.17235/reed.2020.6832/2019

Original

The 100 top cited articles in the field of digestive endoscopy: from 1950 to 2017

DOI: 10.17235/reed.2020.6828/2019

Original

A case-control study demonstrates an improved visualization when capsule endoscopy is performed after preparation with polyethylene glycol and ascorbic acid

DOI: 10.17235/reed.2020.6806/2019

Letter

Perforation of the small bowel secondary to capsule endoscopy retention

DOI: 10.17235/reed.2020.6772/2019

Letter

Gastric syphilis and its importance for a differential diagnosis in HIV patients

DOI: 10.17235/reed.2020.6729/2019

Original

The diagnostic value of video capsule endoscopy for Meckel’s diverticulum in children

DOI: 10.17235/reed.2020.6708/2019

Letter

Gastric ulcer due to mucormycosis in a critical patient

DOI: 10.17235/reed.2020.6636/2019

Letter

Esophagogastroduodenoscopy: how far should we go? A point of view.

DOI: 10.17235/reed.2019.6585/2019

Letter

Temporomandibular joint dislocation after an upper endoscopy: a complication to consider

DOI: 10.17235/reed.2019.6561/2019

Original

Factors associated with the presence of abnormal levels of fecal calprotectin in patients with negative panenteric studies

DOI: 10.17235/reed.2020.6508/2019

Letter

Primary gastric choriocarcinoma

DOI: 10.17235/reed.2020.6478/2019

Letter

Pancreatic metastasis of Merkel-cell carcinoma: a rare neoplasm of the pancreas

DOI: 10.17235/reed.2020.6467/2019

Digestive Diseases Image

Gastrointestinal bleeding due to duodenal mucormycosis in an immunocompetent host mimicking malignancy

DOI: 10.17235/reed.2019.6462/2019

Original

Lewis score: a useful tool for diagnosis and prognosis in Crohn’s disease

DOI: 10.17235/reed.2020.6434/2019

Original

Randomized clinical trial to assess the mPADSS scale in recovery and home discharge after endoscopy

DOI: 10.17235/reed.2020.6420/2019

Digestive Diseases Image

Jejunal schwannoma detected by video capsule endoscopy

DOI: 10.17235/reed.2020.6474/2019

Original

Detection of polyps in the small bowel of patients with acromegaly via capsule endoscopy

DOI: 10.17235/reed.2020.6377/2019

Digestive Diseases Image

Capsule endoscopy, a useful tool for the diagnosis of a tapeworm infection

DOI: 10.17235/reed.2019.6346/2019

Editorial

Endoscopy units – Statu quo

DOI: 10.17235/reed.2019.6347/2019

Letter

Endoscopically diagnosed systemic mastocytosis

DOI: 10.17235/reed.2019.6246/2019

Original

The effect of a preoperative biliary prosthesis on the infectious complications of the pancreaticoduodenectomy

DOI: 10.17235/reed.2019.6228/2019

Letter

Endoscopic balloon dilation in duodenal stenosis secondary to intestinal lymphoma in a heart transplant patient

DOI: 10.17235/reed.2019.6221/2019

Digestive Diseases Image

A rare heterotopic gastric mucosa appearing between the muscularis mucosae and submucosa

DOI: 10.17235/reed.2019.6134/2018

Special Article

Quality indicators in gastroscopy. Gastroscopy procedure

DOI: 10.17235/reed.2019.6023/2018

Letter

Endoscopic management of Boerhaave’s syndrome

DOI: 10.17235/reed.2019.6013/2018

Letter

Pyogenic granuloma of the duodenum as an unusual cause of gastrointestinal bleeding

DOI: 10.17235/reed.2019.5977/2018

Original

Influence of demographic and clinical features of the patient on transit times and impact the on the diagnostic yield of capsule endoscopy

DOI: 10.17235/reed.2019.5971/2018

Digestive Diseases Image

Intraductal papillary mucinous neoplasm of the main duct in a patient with pancreas divisum

DOI: 10.17235/reed.2019.5959/2018

Letter

Use of patency capsule in daily practice

DOI: 10.17235/reed.2019.5952/2018

Original

Bariatric and metabolic endoscopy in the handling of fatty liver disease. A new emerging approach?

DOI: 10.17235/reed.2019.5949/2018

Original

Small bowel transit time of capsule endoscopy as a factor for the detection of lesions in potential small bowel bleeding

DOI: 10.17235/reed.2019.5943/2018

Original

Metastatic tumors in the pancreas: the role of endoscopic ultrasound-guided fine‐needle aspiration

DOI: 10.17235/reed.2019.5914/2018

Digestive Diseases Image

Treatment of gastric GIST using endoscopic techniques combined with the application of endoloop and intralesional cyanoacrylate in a non-surgical patient

DOI: 10.17235/reed.2018.5899/2018

Letter

Multiple biliary hamartomatosis: an endoscopic ultrasound clinical case

DOI: 10.17235/reed.2019.5894/2018

Editorial

Preventing incomplete and inadequately cleansed capsule endoscopy examinations. Is it possible?

DOI: 10.17235/reed.2018.5820/2018

Original

A descriptive monitoring study of a non-anesthetist sedation quality program

DOI: 10.17235/reed.2018.5763/2018

Letter

Symptomatic exfoliative esophagitis induced by dabigatran

DOI: 10.17235/reed.2018.5747/2018

Original

Effectiveness and safety of gastrointestinal endoscopy during a specific sedation training program for non-anesthesiologists

DOI: 10.17235/reed.2018.5713/2018

Special Article

The current situation of digestive endoscopy units in the Valencian Community

DOI: 10.17235/reed.2019.5676/2018

Letter

Factors that predict the presence of non-small bowel lesions during capsule endoscopy examinations

DOI: 10.17235/reed.2018.5666/2018

Special Article

Endoscopy and sedation: an inseparable binomial for the gastroenterologist

DOI: 10.17235/reed.2018.5585/2018

Letter

Intramural esophageal dissection. A rare occurrence in pediatric eosinophilic esophagitis

DOI: 10.17235/reed.2018.5577/2018

Letter to the Editor

Patients’ perspective on sedation during upper gastrointestinal endoscopy. Systematic use of sedation or systematic prior information?

DOI: 10.17235/reed.2018.5546/2018

Special Article

Basic training in digestive endoscopy for resident physicians in gastroenterology. Recommendations by the Sociedad Española de Endoscopia Digestiva (SEED)

DOI: 10.17235/reed.2018.5545/2018

Letter to the Editor

Sedation assisted by an endoscopist (SAE) for complex endoscopic procedures. Is it time to change the current guidelines?

DOI: 10.17235/reed.2018.5537/2018

Letter to the Editor

Safety of propofol sedation directed by endoscopists: how long should we continue to generate evidence?

DOI: 10.17235/reed.2018.5531/2018

Digestive Diseases Image

Dysphagia and hematemesis caused by an intramural esophageal dissection

DOI: 10.17235/reed.2018.5471/2018

Original

Efficacy and safety of transoral outlet reduction via endoscopic suturing in patients with weight regain after a surgical Roux-en-Y gastric bypass

DOI: 10.17235/reed.2018.5419/2017

Original

A clinical trial comparing propofol versus propofol plus midazolam in diagnostic endoscopy of patients with a low anesthetic risk

DOI: 10.17235/reed.2018.5289/2017

Original

Severe cardiorespiratory complications derived from propofol sedation monitored by an endoscopist

DOI: 10.17235/reed.2018.5282/2017

Original

Quality of sedation with propofol administered by non-anesthetists in a digestive endoscopy unit: the results of a one year experience

DOI: 10.17235/reed.2018.5283/2017

Letter to the Editor

Real time visualization may be advisable to exclude aspiration in patients undergoing capsule endoscopy examination

DOI: 10.17235/reed.2017.5244/2017

Original

Sedation with propofol in digestive endoscopy administered by gastroenterologists. Experience in a Venezuelan hospital

DOI: 10.17235/reed.2018.5185/2017

Original

Inter and intra-observer concordance for the diagnosis of portal hypertension gastropathy

DOI: 10.17235/reed.2018.5169/2017

Case Report

Hepatocolic fistula managed with a novel Padlock® device for endoscopic closure

DOI: 10.17235/reed.2017.5150/2017

Letter to the Editor

GETTEMO position statement on bariatric endoscopic techniques as a voluntary medicine

DOI: 10.17235/reed.2017.5144/2017

Original

Can we rely on inflammatory biomarkers for the diagnosis and monitoring Crohn’s disease activity?

DOI: 10.17235/reed.2017.5126/2017

Original

Gastroduodenal lesions detected during small bowel capsule endoscopy: incidence, diagnostic and therapeutic impact

DOI: 10.17235/reed.2017.5114/2017

Original

Economic evaluation of endoscopic radiofrequency ablation for the treatment of dysplastic Barrett’s esophagus in Spain

DOI: 10.17235/reed.2017.5087/2017

Original

Capsule endoscopy with PillCamSB2 versus PillCamSB3: has the improvement in technology resulted in a step forward?

DOI: 10.17235/reed.2017.5071/2017

Case Report

Serrated polyposis syndrome associated with long-standing inflammatory bowel disease

DOI: 10.17235/reed.2017.5068/2017

Special Article

Quality indicators in digestive endoscopy: introduction to structure, process, and outcome common indicators

DOI: 10.17235/reed.2017.5035/2017

Letter to the Editor

In response to the letter by Cabadas and Álvarez-Escudero about the editorial: “Will societies of anesthesiologists partake in the take-off of non-anesthesiologist administration of propofol?”

DOI: 10.17235/reed.2017.4938/2017

Special Article

Spanish consensus document on bariatric endoscopy. Part 2: specific endoscopic treatments

DOI: 10.17235/reed.2019.4922/2017

Digestive Diseases Image

Metastasis of dermatofibrosarcoma diagnosed by capsule endoscopy

DOI: 10.17235/reed.2018.4900/2017

Original

Clinical manifestations and endoscopic presentations of gastric lymphoma: a multicenter seven year retrospective survey

DOI: 10.17235/reed.2017.4882/2017

Original

Continuous esomeprazole infusion versus bolus administration and second look endoscopy for the prevention of rebleeding in children with a peptic ulcer

DOI: 10.17235/reed.2018.4864/2017

Original

Predictive factors of an incomplete examination and inadequate small-bowel cleanliness during capsule endoscopy

DOI: 10.17235/reed.2018.4834/2017

Case Report

Fecal microbiota transplantation in recurrent Clostridium difficile infection in a patient with concomitant inflammatory bowel disease

DOI: 10.17235/reed.2017.4819/2016

Editorial

Will societies of anesthesiologists partake in the take-off of non-anesthesiologist administration of propofol?

DOI: 10.17235/reed.2017.4707/2016

Original

A survey-based analysis on endoscopic quality indicators compliance among Spanish endoscopists

DOI: 10.17235/reed.2016.4705/2016

Letter to the Editor

Symptomatic retention of the Agile® patency capsule

DOI: 10.17235/reed.2017.4691/2016

Original

Validation of SPICE, a method to differentiate small bowel submucosal lesions from innocent bulges on capsule endoscopy

DOI: 10.17235/reed.2017.4629/2016

Digestive Diseases Image

Meckel´s diverticulum bleeding detected by capsule endoscopy

Letter to the Editor

Author´s reply to the letter: In response to the editorial “Sedation in endoscopy in 2016: Is it safe sedation with propofol led by the endoscopist in complex situations?”

DOI: 10.17235/reed.2016.4611/2016

Original

Colonic lesions in patients undergoing small bowel capsule endoscopy: incidence, diagnostic and therapeutic impact

DOI: 10.17235/reed.2017.4604/2016

Review

Diagnostic and therapeutic features of small bowel involvement in portal hypertension

DOI: 10.17235/reed.2017.4596/2016

Digestive Diseases Image

Extrinsic esophageal compression by the vertebral body

Letter to the Editor

Ball valve syndrome caused by a giant gastric Vanek’s tumor

DOI: 10.17235/reed.2017.4526/2016

Letter to the Editor

Laparoscopic treatment of hemorrhagic Meckel diverticulum after diagnosis with wireless capsule endoscopy and double-balloon enteroscopy

DOI: 10.17235/reed.2017.4522/2016

Digestive Diseases Image

An unusual cause of Boerhaave´s syndrome in a young patient

Original

The importance of a second opinion in the diagnosis of Barrett’s esophagus: a “real life” study

DOI: 10.17235/reed.2016.4505/2016

Special Article

Spanish Consensus Document on Bariatric Endoscopy. Part 1. General considerations

DOI: 10.17235/reed.2018.4503/2016

Original

Multicenter study on the safety of bariatric endoscopy

DOI: 10.17235/reed.2017.4499/2016

Letter to the Editor

Endoscopic removal of a hashish packet

DOI: 10.17235/reed.2017.4504/2016

Original

The use of a segmental endoscopic score may improve the prediction of clinical outcomes in acute severe ulcerative colitis

DOI: 10.17235/reed.2016.4470/2016

Letter to the Editor

In response to the editorial “Sedation in endoscopy in 2016: Is it safe sedation with propofol led by the endoscopist in complex situations?”

DOI: 10.17235/reed.2016.4471/2016

Letter to the Editor

Fecal microbiota transplantation: is there a role in the eradication of carbapenem-resistant Klebsiella pneumoniae intestinal carriage?

DOI: 10.17235/reed.2017.4425/2016

Original

Antiplatelet agents and/or anticoagulants are not associated with worse outcome following nonvariceal upper gastrointestinal bleeding

DOI: 10.17235/reed.2016.4424/2016

Digestive Diseases Image

Hemolymphangioma as a cause of overt obscure gastrointestinal bleeding: a case report

Original

Therapeutic impact of colon capsule endoscopy with PillCam™ COLON 2 after incomplete standard colonoscopy: a Spanish multicenter study

DOI: 10.17235/reed.2017.4369/2016

Original

Validation of the computed assessment of cleansing score with the Mirocam® system

DOI: 10.17235/reed.2016.4366/2016

Letter to the Editor

Whipple’s disease under the vision of capsule endoscopy

DOI: 10.17235/reed.2016.4362/2016

Letter to the Editor

Asymptomatic bronchial aspiration of capsule endoscope: a significant complication

DOI: 10.17235/reed.2016.4363/2016

Digestive Diseases Image

Signet ring cell carcinoma of the jejunum: an uncommon finding within the reach of capsule endoscopy

Letter to the Editor

Author´s reply: About human taeniasis and Taenia saginata diagnosis by endoscopy

DOI: 10.17235/reed.2016.4339/2016

Original

Fecal calprotectin and C-reactive protein are associated with positive findings in capsule endoscopy in suspected small bowel Crohn’s disease

DOI: 10.17235/reed.2016.4318/2016

Editorial

Sedation for endoscopy in 2016 — Is endoscopist-guided sedation safe in complex situations?

DOI: 10.17235/reed.2016.4383/2016

Letter to the Editor

About human taeniasis and Taenia saginata diagnosis by endoscopy

DOI: 10.17235/reed.2016.4297/2016

Digestive Diseases Image

Jejunal metastasis of renal cell carcinoma

Case Report

Colonic obstruction secondary to sigmoid fecaloma endoscopically resolved with Coca-Cola®

DOI: 10.17235/reed.2017.4209/2016

Original

Safety and risk factors for difficult endoscopist-directed ERCP sedation in daily practice: a hospital-based case-control study

DOI: 10.17235/reed.2016.4206/2016

Original

Endoscopic colostomy with percutaneous colopexy: an animal feasibility study

DOI: 10.17235/reed.2017.4201/2016

Case Report

Pyogenic granuloma in the jejunum successfully removed by single-balloon enteroscopy

DOI: 10.17235/reed.2017.4153/2015

Letter to the Editor

Transanal submucosal endoscopic resection (TASER) by TEO system®

DOI: 10.17235/reed.2016.4154/2015

Editorial

Obscure gastrointestinal bleeding and “obscure” capsule. May we switch on any lights?

DOI: 10.17235/reed.2015.4124/2015

Original

Endoscopic sleeve gastroplasty (the Apollo method): a new approach to obesity management

DOI: 10.17235/reed.2016.3988/2015

Original

Predictive factors of small bowel patency in Crohn's disease patients

DOI: 10.17235/reed.2015.3957/2015

Editorial

Prevention of post-operative recurrence in Crohn´s disease. Are we ready for a treat-to-target strategy?

DOI: 10.17235/reed.2015.3990/2015

Original

Guideline for wireless capsule endoscopy in children and adolescents: A consensus document by the SEGHNP (Spanish Society for Pediatric Gastroenterology, Hepatology, and Nutrition) and the SEPD (Spanish Society for Digestive Diseases)

DOI: 10.17235/reed.2015.3921/2015

Digestive Diseases Image

A typical but seldom recognized foreign body in the esophagus of a laryngectomized patient

Digestive Diseases Image

Gastric inflammatory fibroid polyp mimicking a gastrointestinal stromal tumour

Original

What is the long-term outcome of a negative capsule endoscopy in patients with obscure gastrointestinal bleeding?

DOI: 10.17235/reed.2015.3900/2015

Original

Neomycin and bacitracin reduce the intestinal permeability in mice and increase the expression of some tight-junction proteins

DOI: 10.17235/reed.2015.3868/2015

Original

Comparative study between open and minimally invasive approach in the surgical management of esophageal leiomyoma

DOI: 10.17235/reed.2015.3845/2015

Original

Impact of endoscopic monitoring in postoperative Crohn’s disease patients already receiving pharmacological prevention of recurrence

DOI: 10.17235/reed.2015.3836/2015

Original

Incidence, clinical outcomes, and therapeutic approaches of capsule endoscopy-related adverse events in a large study population

DOI: 10.17235/reed.2015.3820/2015

Review

Management of antiplatelet and anticoagulant therapy for endoscopic procedures: Introduction to novel oral anticoagulants

DOI: 10.17235/reed.2016.3811/2015

Original

Fully covered metal stents for the treatment of leaks after gastric and esophageal surgery

DOI: 10.17235/reed.2015.3765/2015

Case Report

Atypical diagnosis diagnosis by endoscopic capsule: Whipple´s disease

DOI: 10.17235/reed.2015.3718/2015

Case Report

Endoscopy as a diagnostic and therapeutic alternative technique of taeniasis

DOI: 10.17235/reed.2015.3585/2014

Digestive Diseases Image

Jejunal plasmablastic lymphoma presenting as obscure overt gastrointestinal bleeding - diagnosis by wireless capsule endoscopy

Citation tools
Ponte A, Pinho R, Mota M, Silva J, Vieira N, Oliveira R, et all. Fecal microbiota transplantation in refractory or recurrent Clostridium difficile infection: a real-life experience in a non-academic center. 5099/2017


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 1276 visits.
This article has been downloaded 310 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 02/06/2017

Accepted: 15/12/2017

Online First: 07/02/2018

Published: 27/04/2018

Article revision time: 192 days

Article Online First time: 250 days

Article editing time: 329 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Home
Articles
Current issues
Previous issues
Most read articles
Clinical guidelines
Reviews
Topic collection
Submit a manuscript
Submit a manuscript
Information for authors
Language editing services
Editorial time – Publication time
REED awards
ORCID guide
PubMed guide
Journal info
About the journal
Editorial board
For reviewers
For advertisers
REED centenary
Open access
Articles in press
Home
Articles
Current issues
Previous issues
Most read articles
Clinical guidelines
Reviews
Topic collection
Submit a manuscript
Submit a manuscript
Information for authors
Language editing services
Editorial time – Publication time
REED awards
ORCID guide
PubMed guide
Journal info
About the journal
Editorial board
For reviewers
For advertisers
REED centenary
Open access
Articles in press
Home
Articles
Current issues
Previous issues
Most read articles
Clinical guidelines
Reviews
Topic collection
Submit a manuscript
Submit a manuscript
Information for authors
Language editing services
Editorial time – Publication time
REED awards
ORCID guide
PubMed guide
Journal info
About the journal
Editorial board
For reviewers
For advertisers
REED centenary
Open access
Articles in press
Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology