Year 2015 / Volume 107 / Number 10
Editorial
Prevention of post-operative recurrence in Crohn´s disease. Are we ready for a treat-to-target strategy?

583-585

DOI: 10.17235/reed.2015.3990/2015

Vicent Hernández Ramírez,

Abstract
Crohn’s disease (CD) is chronic inflammatory bowel disease leading to progressive loss of intestinal function and disability mainly due to the need of surgical treatment in a high proportion of patients.
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References
1. Pariente B, Cosnes J, Danese S et al. Development of the Crohn’s disease digestive damage score, the Lémann score. Inflamm Bowel Dis 2011;17:1415–22. DOI: 10.1002/ibd.21506
2. Rutgeerts P, Geboes K, Vantrappen G et al. Predictability of the postoperative course of Crohn’s disease. Gastroenterology 1990;99:956–63. doi: S0016508590003596 [pii]
3. Van Assche G, Dignass A, Reinisch W, et al. The second European evidence-based Consensus on the diagnosis and management of Crohn’s disease: Special situations. Journal of Crohn’s and Colitis 2010; 4:63-101. DOI: 10.1016/j.crohns.2009.09.009
4. De Cruz P, Kamm MA, Prideaux L et al. Postoperative recurrent luminal Crohn’s disease: A systematic review. Inflamm Bowel Dis 2012;18:758–77. DOI: 10.1002/ibd.21825
5. Schwartz M, Regueiro M. Prevention and treatment of postoperative Crohn’s disease recurrence: An update for a new decade. Curr Gastroenterol Rep 2011;13:95–100. DOI: 10.1007/s11894-010-0152-x
6. Sorrentino D. State-of-the-art medical prevention of postoperative recurrence of Crohn’s disease. Nat Rev Gastroenterol Hepatol 2013;10:413–22. DOI: 10.1038/nrgastro.2013.69
7. Sandborn WJ, Hanauer S, Van Assche G, et al. Treating beyond symptoms with a view to improving patient outcomes in inflammatory bowel diseases. J Crohn’s Colitis. European Crohn’s and Colitis Organisation 2014;8:927–35. DOI: 10.1016/j.crohns.2014.02.021
8. Rutgeerts P, Hiele M, Geboes K, et al. Controlled trial of metronidazole treatment for prevention of Crohn’s recurrence after ileal resection. Gastroenterology 1995;108:1617–21. DOI: 10.1016/0016-5085(95)90121-3
9. Peyrin-Biroulet L, Deltenre P, Ardizzone S, et al. Azathioprine and 6-mercaptopurine for the prevention of postoperative recurrence in Crohn’s disease: a meta-analysis. Am J Gastroenterol 2009;104:2089–96. DOI: 10.1038/ajg.2009.301
10. Carla-Moreau A, Paul S, Roblin X, et al. Prevention and treatment of postoperative Crohn’s disease recurrence with anti-TNF therapy: a meta-analysis of controlled trials. Dig Liver Dis 2015;47:191–6. DOI: 10.1016/j.dld.2014.11.005
11. Domènech E, Mañosa M, Bernal I et al. Impact of azathioprine on the prevention of postoperative Crohn’s disease recurrence: Results of a prospective, observational, long-term follow-up study. Inflamm Bowel Dis 2008;14:508–13. DOI: 10.1002/ibd.20359
12. De Cruz P, Kamm MA, Hamilton AL et al. Crohn’s disease management after intestinal resection: a randomised trial. Lancet 2015;385:1406-17. DOI: 10.1016/S0140-6736(14)61908-5 DOI: 10.1016/S0140-6736(14)61908-5
13. Ferrante M, Papamichael K, Duricova D et al. Systematic versus Endoscopy-driven Treatment with Azathioprine to Prevent Postoperative Ileal Crohn’s Disease Recurrence. J Crohn’s Colitis 2015;9:617–24. DOI: 10.1093/ecco-jcc/jjv076
14. Baudry C, Pariente B, Lourenço N et al. Tailored treatment according to early post-surgery colonoscopy reduces clinical recurrence in Crohn’s disease: A retrospective study. Dig Liver Dis 2014;887–92. DOI: 10.1016/j.dld.2014.07.005
15. González Lama Y. Impact of Endoscopic monitoring in postoperative Crohn’s disease patients already receiving pharmacological prevention of recurrence. Rev Esp Enferm Dig. 2015 Jul 14;107. DOI: 10.17235/reed.2015.3836/2015
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Hernández Ramírez V. Prevention of post-operative recurrence in Crohn´s disease. Are we ready for a treat-to-target strategy?. 3990/2015


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Publication history

Received: 01/09/2015

Accepted: 02/09/2015

Online First: 08/09/2015

Published: 25/09/2015

Article Online First time: 7 days

Article editing time: 24 days


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