Year 2023 / Volume 115 / Number 7
Letter
A rare case of ulcerative colitis following Bacillus Calmette-Guérin therapy

403

DOI: 10.17235/reed.2022.9191/2022

Joel Ferreira Silva, Pedro Pereira, Guilherme Macedo,

Abstract
A 60-years-old male was referred to us due to frequent discharge of blood and mucus during the last 2 months. The patient had a history of bladder cancer and was under therapy with intra-vesical Bacillus Calmette Guerin (BCG) for the last 4 months. Colonoscopy revealed loss of vascular pattern, erythematous appearance, granularity, and friability in the mucosa of the distal rectum.
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References
1. Gandhi NM, Morales A, Lamm DL. Bacillus Calmette-Guérin immunotherapy for genitourinary cancer. BJU Int 2013;112(3):288-97. 10.1111/j.1464-410X.2012.11754.x
2. Satgé D, Pommepuy I, Hassan T, et al. Ulcerative terminal ileitis after BCG therapy for bladder carcinoma. Histopathology 2002;41(3):266-8. 10.1046/j.1365-2559.2002.01445.x
3. Pizzi M, Albertoni L, Stefanizzi L, et al. Gastrointestinal Crohn-like disease following BCG therapy. Int J Colorectal Dis 2015;30(12):1745-6. 10.1007/s00384-015-2157-2
4. Makharia GK, Srivastava S, Das P, et al. Clinical, endoscopic, and histological differentiations between Crohn's disease and intestinal tuberculosis. Am J Gastroenterol 2010;105(3):642-51. 10.1038/ajg.2009.585
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Silva J, Pereira P, Macedo G. A rare case of ulcerative colitis following Bacillus Calmette-Guérin therapy. 9191/2022


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Publication history

Received: 07/09/2022

Accepted: 03/11/2022

Online First: 10/11/2022

Published: 06/07/2023

Article revision time: 51 days

Article Online First time: 64 days

Article editing time: 302 days


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