Year 2024 / Volume 116 / Number 1
Original
Dried lemon slices improve bowel cleansing quality of polyethylene glycol for colonoscopy preparation: randomized controlled trial

7-13

DOI: 10.17235/reed.2023.9676/2023

Xiawei Huang, Liping Yang, Yingbo Lyu, Han Ma, Xiaoli Zhou, Kexin Ye, Jiehui Feng,

Abstract
Background: adequate bowel preparation is related to the quality of colonoscopy. Dried lemon slices can increase gastrointestinal peristalsis, which has shown potential as an adjuvant of bowel preparation. We hypothesized that the combination of dried lemon slices and polyethylene glycol (PEG) could improve the efficacy of bowel preparation and be more acceptable to participants. Aim: to investigate the effectiveness of lemon slices combined with PEG for colonoscopy preparation. Methods: a prospective, single-center, randomized, controlled trial was performed of 521 patients randomly assigned to two groups. A total of 254 patients were given lemon slices based on conventional 4-L PEG treatment for the bowel, while 267 patients received only 4-L PEG treatment. Patients’ basic information, procedure-related parameters, adverse effects, and subjective feelings were collected by questionnaires. Intestinal tract cleanliness was scored according to the Boston Bowel Preparation Scale (BBPS) by experienced endoscopists. Data were analyzed by the two-sample t-test or the Chi-squared test. Results: the BBPS scores were significantly higher in the PEG + lemon slice group (p < 0.05). The taste acceptability, satisfaction, and willingness to repeat bowel preparation were significantly higher in the PEG+ lemon slice group (p < 0.05). However, a larger proportion of patients from the PEG+ lemon slice group (30.7 %) suffered abdominal distension compared with the PEG group (20.6 %), while the incidence of other adverse effects was comparable between the two groups. Conclusion: the addition of dried lemon slices to conventional PEG showed its superiority for bowel preparation.
Lay Summary
Colonoscopy is widely used in clinical practice, however, many patients suffer from the bowel preparation process before colonoscopy. This study aimed to investigate the effectiveness of lemon slices combined with PEG for colonoscopy preparation, which could possibly improve the taste of laxatives and make patients feel better during the process. We randomly divided participants into two group to receive conventional bowel preparation formula and a new formula with lemon slices separately. The bowel preparation quality, adverse effects and patients’ objective feelings were evaluated during or after the process. The application of lemon slices combined with conventional polyethylene glycol treatment provided a novel method for bowel preparation with higher quality of bowel cleanness compared with conventional treatment. In addition, it improved the taste of laxatives and showed higher acceptability. Hence, it is a practical and simple bowel preparation method demonstrating its potential in clinical practice.
Share Button
New comment
Comments
No comments for this article
Related articles

Digestive Diseases Image

Underwater polypectomy at the appendiceal orifice in a patient on anticoagulation

DOI: 10.17235/reed.2023.9842/2023

Letter

An uncommon colonic polyp

DOI: 10.17235/reed.2022.9160/2022

Digestive Diseases Image

Intestinal obstruction due to bariolith impaction

DOI: 10.17235/reed.2022.9084/2022

Letter

Anorectal malignant melanoma, a diagnostic challenge

DOI: 10.17235/reed.2022.9068/2022

Letter

Lead ingestion, medical emergency and action plan

DOI: 10.17235/reed.2022.9048/2022

Letter

Endoscopic findings of radiation ileitis

DOI: 10.17235/reed.2022.9036/2022

Letter

Endoscopic imaging of pneumatosis intestinalis

DOI: 10.17235/reed.2022.8972/2022

Editorial

Colonoscopy — When quality matters

DOI: 10.17235/reed.2022.8942/2022

Digestive Diseases Image

Colonic Kaposi’s sarcoma as the first clinical manifestation of undiagnosed HIV

DOI: 10.17235/reed.2022.8717/2022

Letter

Gastrointestinal lymphoma, a rare endoscopic lesion

DOI: 10.17235/reed.2022.8555/2021

Letter

Cecal MALT lymphoma: a challenging diagnosis

DOI: 10.17235/reed.2021.8526/2021

Letter

Surprises in cecal intubation: foreign bodies in the colon

DOI: 10.17235/reed.2021.8155/2021

Digestive Diseases Image

Phlebosclerotic colitis: an unusual cause of abdominal pain and hematochezia

DOI: 10.17235/reed.2020.7358/2020

Case Report

Primary colon mantle lymphoma: a misleading macroscopic appearance!

DOI: 10.17235/reed.2019.6405/2019

Digestive Diseases Image

Colorectal penetration by two intrauterine devices

DOI: 10.17235/reed.2019.5974/2018

Editorial

Colorectal cancer screening and survival

DOI: 10.17235/reed.2018.5870/2018

Letter

Bacterial endogenous endophthalmitis after colonoscopy

DOI: 10.17235/reed.2018.5658/2018

Review

Quality indicators in colonoscopy. The colonoscopy procedure

DOI: 10.17235/reed.2018.5408/2017

Letter to the Editor

A rare complication after colonoscopy: a splenic rupture

DOI: 10.17235/reed.2018.5362/2017

Letter to the Editor

Acute appendicitis after a colonic endoscopic submucosal resection

DOI: 10.17235/reed.2018.5307/2017

Digestive Diseases Image

Contribution of the virtual colonoscopy in a case of intestinal intussusception

DOI: 10.17235/reed.2017.5261/2017

Digestive Diseases Image

A bull horn fragment found on colonoscopy

DOI: 10.17235/reed.2017.5020/2017

Editorial

Issue pending: minimizing anxiety before colonoscopy

DOI: 10.17235/reed.2016.4756/2016

Digestive Diseases Image

Intrauterine device in the rectal cavity

Letter to the Editor

Primary chancre in the rectum: an underdiagnosed cause of rectal ulcer

DOI: 10.17235/reed.2017.4457/2016

Digestive Diseases Image

Pneumatosis cystoides intestinalis

Letter to the Editor

Splenic rupture after colorectal cancer screening

DOI: 10.17235/reed.2015.3714/2015

Citation tools
Huang X, Yang L, Lyu Y, Ma H, Zhou X, Ye K, et all. Dried lemon slices improve bowel cleansing quality of polyethylene glycol for colonoscopy preparation: randomized controlled trial. 9676/2023


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 1426 visits.
This article has been downloaded 139 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 19/04/2023

Accepted: 06/07/2023

Online First: 04/08/2023

Published: 11/01/2024

Article revision time: 71 days

Article Online First time: 107 days

Article editing time: 267 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2024 y Creative Commons. The Spanish Journal of Gastroenterology