Year 2023 / Volume 115 / Number 4
Letter
Colonic perineurioma of the transverse colon: presentation of a rare neoplasm in an atypical location

221

DOI: 10.17235/reed.2023.9440/2022

Emanuel Dias, Marco Antonio Silva, João Carlos Almeida, Jorge Pinheiro, Guilherme Macedo,

Abstract
A 51-year-old male with previous medical history of dyslipidemia performed screening colonoscopy, which revealed a sessile polypoid lesion with a diameter of approximately 8 mm located at the proximal transverse colon, which was resected en bloc with a cold snare. Remarkably, histopathological examination revealed a proliferation of spindle cells in the lamina propria entrapping colonic crypts without evidence of nuclear pleomorphism, mitotic figures or necrosis. On immunohistochemistry, spindle cells were diffusely positive for glucose transporter-1 and negative for S100, DOG1, CD34 and smooth muscle actin. These features were consistent with a diagnosis of colonic perineurioma.
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References
1. Eslami-Varzaneh F, Washington K, Robert ME, Kashgarian M, Goldblum JR, Jain D. Benign fibroblastic polyps of the colon: a histologic, immunohistochemical, and ultrastructural study. Am J Surg Pathol. 2004;28:374–8.
2. Kamionkowski S, Issak A, Zhang C, Wang Y, Kyprianou A. A solitary sigmoid perineurioma in an otherwise healthy 30-Year-Old male. Cureus. 2021;13(5):e15104.
3. van Wyk AC, van Zyl H, Rigby J. Colonic perineurioma (benign fibroblastic polyp): case report and review of the literature. Diagn Pathol. 2018;13(1):16.
4. McCarthy AJ, Karamchandani DM, Chetty R. Neural and neurogenic tumours of the gastroenteropancreaticobiliary tract. Journal of Clinical Pathology. 2018;71:565-578.
5. García IC, Romero IL, Prián RMM, Morillas DR. Importance of immunohistochemistry in the differential diagnosis of gastric stromal tumors: GIST vs. schwannoma. Rev Esp Enferm Dig. 2022;114(5):305-306.
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Dias E, Silva M, Almeida J, Pinheiro J, Macedo G. Colonic perineurioma of the transverse colon: presentation of a rare neoplasm in an atypical location. 9440/2022


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Publication history

Received: 23/12/2022

Accepted: 01/01/2023

Online First: 16/01/2023

Published: 03/04/2023

Article Online First time: 24 days

Article editing time: 101 days


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