Year 2023 / Volume 115 / Number 11
Letter
A case of complex hemangioendothelioma of the liver in an infant

668-670

DOI: 10.17235/reed.2023.9949/2023

Wenpeng Huang, Liming Li, Jianbo Gao, Lei Kang,

Abstract
A physical examination of a 9-month-old female infant presenting with vomiting and diarrhea revealed tenderness in the right upper abdomen and heightened abdominal muscle tone. Abdominal ultrasonography identified an irregular hypoechoic area within the right lobe of the liver. While a subsequent enhanced CT examination disclosed a well-defined lesion exhibiting internal focal calcification and delayed heterogeneous enhancement. Subsequently, she underwent surgical resection, and postoperative pathology revealed areas of epithelioid hemangioendothelioma and cavernous hemangioma. Immunohistochemistry demonstrated positive expression of CD34, CD31, FLI-1, and F-VIII. The pathologic diagnosis was confirmed as composite hemangioendothelioma (CHE).
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References
[1] Nakamura S, Uehara M, Kobayashi S, et al. Composite hemangioendothelioma in the cervical spine with kaposiform hemangioendothelioma features in an elderly patient: a case report[J]. BMC Geriatr, 2022, 22(1):952. DOI: 10.1186/s12877-022-03677-1.
[2] Zhang J, Wu B, Zhou GQ, et al. Composite hemangioendothelioma arising from the kidney: case report with review of the literature[J]. Int J Clin Exp Pathol, 2013, 6(9):1935-1941.
[3] Cifrián Canales I, García Bernardo CM, Contreras Saiz E. Hepatic epithelioid hemangioendothelioma: a rare vascular tumor with an unpredictable diagnosis[J]. Rev Esp Enferm Dig, 2021, 113(4):300-301. DOI: 10.17235/reed.2020.7318/2020.
[4] Alventosa Mateu C, Urquijo Ponce JJ, Herráez Cervera B, et al. Epithelioid hemangioendothelioma: a rare cause of a liver tumor[J]. Rev Esp Enferm Dig, 2021, 113(1):69-70. DOI: 10.17235/reed.2020.7127/2020.
[5] Utaş S, Canöz O, Ferahbaş A, et al. Composite cutaneous haemangioendothelioma treated with interferon[J]. J Eur Acad Dermatol Venereol, 2008, 22(4):503-505. DOI: 10.1111/j.1468-3083.2007.02366.x.
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Huang W, Li L, Gao J, Kang L. A case of complex hemangioendothelioma of the liver in an infant. 9949/2023


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Publication history

Received: 10/09/2023

Accepted: 14/09/2023

Online First: 29/09/2023

Published: 13/11/2023

Article Online First time: 19 days

Article editing time: 64 days


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