Year 2022 / Volume 114 / Number 4
Letter
Gastric ulcer with liver penetration

248-249

DOI: 10.17235/reed.2022.8528/2021

Emanuel Dias, Hélder Cardoso, Catarina Costa, Guilherme Macedo,

Abstract
A 54-year-old male with previous history of chronic hepatitis C complained of postprandial epigastric discomfort and weight loss. Esophagogastroduodenoscopy revealed a large gastric ulcer on the lesser antral curvature, with biopsies showing granulation tissue and inflammatory activity without other significant changes. Despite therapy with double-dose proton pump inhibitor, the ulcer had not healed or diminished in size at reevaluation endoscopy eight weeks later. Biopsies were repeated and again only revealed granulation tissue and inflammation. The patient undergone partial gastrectomy where fibrotic adhesions to liver and peritoneum were noted. Remarkably, macroscopical analysis of the surgical specimen revealed an hepatic fragment adherent to the ulcer and histopathological examination was consistent with liver penetration. Liver penetration is a rare but important complication that must be considered in the differential diagnosis of medically refractory gastric ulcers, even in the absence of hepatic tissue in endoscopic biopsies.
Share Button
New comment
Comments
No comments for this article
References
1. Matsuzaka S, Nagai Y, Hoshi T, et al. Visible Liver from Huge Gastric Penetration. Intern Med. 2018; 57(11): 1667-8.
2. Kayacetin E, Kayacetin S. Gastric ulcer penetrating to liver diagnosed by endoscopic biopsy. World J Gastroenterol. 2004; 10(12): 1838-40.
3. Stylianopoulou L, Bartsokas C, Kalliakmanis V. Gastric ulcer penetration into liver: A case presentation and review of the literature. Clin Case Rep. 2021; 9(1): 282-5.
Related articles

Digestive Diseases Image

Gastric calcinosis ulcer in a renal transplanted patient

DOI: 10.17235/reed.2023.9495/2023

Letter

A large perforated gastric ulcer due to cocaine use

DOI: 10.17235/reed.2022.8676/2022

Digestive Diseases Image

Bezoar: an uncommon cause of upper gastrointestinal bleeding

DOI: 10.17235/reed.2021.8311/2021

Citation tools
Dias E, Cardoso H, Costa C, Macedo G. Gastric ulcer with liver penetration. 8528/2021


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 1681 visits.
This article has been downloaded 204 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 14/12/2021

Accepted: 22/12/2021

Online First: 10/01/2022

Published: 07/04/2022

Article Online First time: 27 days

Article editing time: 114 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology