Year 2019 / Volume 111 / Number 1
Letter
Fulminant liver failure secondary to submassive hepatic necrosis in a patient treated with Orlistat. A case report

83

DOI: 10.17235/reed.2018.5740/2018

Luis Alberto Martínez Insfran, Felipe Alconchel Gago, Pascual Parrilla Paricio,

Abstract
Orlistat is an intestinal lipase inhibitor drug that is recommended in obese patients along with a hypocaloric diet. Although the most frequent secondary effect is steatorrhea, fulminant liver failure has also been associated with this drug, which has required liver transplantation in 3 patients. We present the case of a 42-year-old obese male.
Share Button
New comment
Comments
No comments for this article
References
1. Torgerson JS, Boldrin MN, Hauptman J, Sjöström L. XENical in the prevention of diabetes in obese subjects (XENDOS) study. Diabetes Care 2004; 27: 155–161.
2. Montero JL, Muntane J, Fraga E et al. Orlistat associated subacute hepatic failure. J Hepatol 2001; 34: 173–179.
3. Thurairajah PH, Syn WK, Neil DA, Stell D, Haydon G. Orlistat (Xenical)-induced subacute liver failure. Eur J Gastroenterol Hepatol 2005; 17: 1437–1438.
4. Wilson NS, Shah N, Manitpisitkul W et al. Liver failure requiring transplantation after orlistat use. Pharmacotherapy 2011; 31: 492–495.
Related articles

Letter

Abernethy syndrome as a cause of liver transplantation

DOI: 10.17235/reed.2024.10561/2024

Digestive Diseases Image

Posterior reversible encephalopathy syndrome (PRES) in post liver transplantation

DOI: 10.17235/reed.2022.8694/2022

Letter

Ertapenem neurotoxicity in liver transplantation

DOI: 10.17235/reed.2021.8469/2021

Digestive Diseases Image

Ischemic cholangiopathy following hepatic artery pseudoaneurysm with thrombosis

DOI: 10.17235/reed.2021.8395/2021

Letter

EBVMCU in a liver-transplant patient

DOI: 10.17235/reed.2021.8064/2021

Digestive Diseases Image

Percutaneous treatment of a splenorenal shunt with an atrial septal closure device

DOI: 10.17235/reed.2020.7701/2020

Review

Physical frailty in liver transplantation

DOI: 10.17235/reed.2020.7448/2020

Letter

Management of hepatic artery aneurysms

DOI: 10.17235/reed.2020.7219/2020

Digestive Diseases Image

Epithelioid hemangioendothelioma: a rare cause of a liver tumor

DOI: 10.17235/reed.2020.7127/2020

Letter to the Editor

Post-transplant lymphoproliferative disease after liver transplantation

DOI: 10.17235/reed.2017.5387/2017

Letter to the Editor

Liver metastasis from colorectal cancer 12 years after liver transplantation

DOI: 10.17235/reed.2017.4507/2016

Citation tools
Martínez Insfran L, Alconchel Gago F, Parrilla Paricio P. Fulminant liver failure secondary to submassive hepatic necrosis in a patient treated with Orlistat. A case report. 5740/2018


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 1208 visits.
This article has been downloaded 317 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 22/05/2018

Accepted: 13/06/2018

Online First: 16/10/2018

Published: 17/01/2019

Article Online First time: 147 days

Article editing time: 240 days


Share
This article has been rated by 1 readers.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology