Year 2021 / Volume 113 / Number 4
Letter
Acute hepatocellular drug-induced liver injury probably caused by doxazosin

301-302

DOI: 10.17235/reed.2020.7268/2020

Javier Jiménez Sánchez, Lidia Serrano Díaz, Juan José Martínez Crespo,

Abstract
Drug-induced liver injury (DILI) is a diagnostic challenge, due to the hepatotoxic potential of drugs, herbs and dietary supplements, the variety of pathological phenotypes and the absence of specific biomarkers.
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References
1. LiverTox: Clinical and Research Information on DrugInduced Liver Injury [Internet]. Doxazosin. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012- [actualizado 8 de enero de 2018; consultado 13 de marzo de 2020]. Disponible en: https://www.ncbi.nlm.nih.gov/books/NBK548718/
2. Agencia Española de Medicamentos y Productos Sanitarios [sede Web]. Fecha técnica Doxazosina 2 mg. Madrid: Agencia Española de Medicamentos y Productos Sanitarios; 2016 [consultado el 13 de marzo de 2020]. Disponible en: https://cima.aemps.es/cima/dochtml/ft/63789/FT_63789.html
3. Cicek T, Gokturk HS, Unler GK. Acute hepatocellular drug induced liver injury probably by alfuzosin. Case Rep Urol. 2015: 101062.
4. Danan G, Benichou C. Causality assessment of adverse reactions to drugs. I. A novel method based on the conclusions of international consensus meetings: application to druginduced liver injuries. J Clin Epidemiol. 1993; 46(11): 1323-1330.
5. Andrade RJ, Aithal GP, Bjornsson ES, et al. EASL Clinical practices guidelines: Drug-induced liver injury. J Hepatol. 2019; 70(6): 1222-1261.
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Jiménez Sánchez J, Serrano Díaz L, Martínez Crespo J. Acute hepatocellular drug-induced liver injury probably caused by doxazosin. 7268/2020


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Publication history

Received: 15/05/2020

Accepted: 09/06/2020

Online First: 20/11/2020

Published: 07/04/2021

Article revision time: 19 days

Article Online First time: 189 days

Article editing time: 327 days


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