Year 2023 / Volume 115 / Number 4
Original
A slowdown of hepatitis C diagnosis in high-prevalence groups and with decentralized diagnostic strategies during the COVID-19 pandemic

175-180

DOI: 10.17235/reed.2022.8412/2021

Dalia Morales-Arráez, Federica Benítez-Zafra, Felicitas Díaz-Flores, María Jesús Medina-Alonso, Luz Goretti Santiago, Víctor Pérez-Pérez, Fernando Gutiérrez-Nicolás, Manuel Hernández-Guerra,

Abstract
Introduction: the COVID-19 pandemic has had a major impact on hepatitis C virus (HCV) diagnosis by hindering the path to elimination. Albeit, in an uneven manner, depending on the risk group and diagnostic strategy. Methods: the requests of antibodies/RNA by venipuncture at hospitals and Primary Care centers (centralized) and via venipuncture or dried blood spot tests at prison and drug treatment centers referred for central processing (integrated decentralized) were recorded for one year, before and after the onset of the COVID-19 health crisis. Results: a total of 20,600 tests (51 % male, 47.9 ± 1 5.8 years) were recorded. Among them, 96.5 % of the cases came from centralized and 3.5 % from decentralized settings, with an active infection rate of 0.2 % and 2.3 % (p < 0.001), respectively. There was a 31.3 % decrease in the number of requests during the pandemic compared to the pre-pandemic period, which was more pronounced in the decentralized than centralized diagnosis setting (60 vs 30 %, p < 0.001). In addition, there was a 31.5 % decline in screening and 18.2 % decrease in the diagnosis of new cases of active infection, with a statistically significant decrease in decentralized compared to centralized diagnosis. Conclusions: during the COVID-19 pandemic, a decline in HCV diagnostic effort was observed, especially in decentralized strategies, with a higher prevalence of infection. Our results suggest a diagnostic delay that will prevent Spain from reaching the elimination target in 2023. Therefore, the reactivation of strategies, particularly targeting the priority groups, is urgently required.
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References
1. European Association for the Study of the Liver. Electronic address: easloffice@easloffice.eu; Clinical Practice Guidelines Panel: Chair:; EASL Governing Board representative:; Panel members:. EASL recommendations on treatment of hepatitis C: Final update of the series☆. J Hepatol. 2020;73(5):1170-1218. DOI: 10.1016/j.jhep.2020.08.018
2. Morales-Arraez D, Nieto Bujalance Y, Diaz-Flores F, et al. Risk of liver fibrosis progression in patients with suboptimal diagnosis of hepatitis C virus infection. Eur J Gastroenterol Hepatol. 2020;32(4):528-534.
3. WHO. Global health sector strategy on viral hepatitis 2016–2021, Towards ending viral hepatitis. Geneva, Switzerland: World Health Organization June; 2016.
4. Plan Estratégico para el abordaje de la Hepatitis C en el SNS (PEAHC). Ministerio de Sanidad, Consumo y Bienestar Social. October 2020. Available in: https://www.mscbs.gob.es/ciudadanos/enfLesiones/enfTransmisibles/hepatitisC/PlanEstrategicoHEPATITISC/docs/Plan_Estrategico_Abordaje_ Hepatitis_C_(PEAHC).pdf.
5. Crespo J, Albillos A, Buti M, et al. Elimination of hepatitis C. Positioning document of the Spanish Association for the Study of the Liver (AEEH). Rev Esp Enferm Dig. 2019;111(11):862-873. DOI: 10.17235/reed.2019.6700/2019
6. Razavi H, Sanchez Gonzalez Y, Yuen C, et al. Global timing of hepatitis C virus elimination in high-income countries. Liver Int. 2020;40(3):522-529.
7. Bedford J, Enria D, Giesecke J, et al. COVID-19: towards controlling of a pandemic. Lancet 2020;395:1015-1018.
8. Crespo J, Iglesias-García J, Hinojosa Del Val JE, et al. COVID-19 and the digestive system: protection and management during the SARS-CoV-2 pandemic. Rev Esp Enferm Dig. 2020;112(5):389-396.
9. Crespo J, Fernández Carrillo C, Iruzubieta P, et al. Massive impact of coronavirus disease 2019 pandemic on gastroenterology and hepatology departments and doctors in Spain. J Gastroenterol Hepatol. 2021;36(6):1627-1633.
10. Sperring H, Ruiz-Mercado G, Schechter-Perkins EM. Impact of the 2020 COVID-19 Pandemic on Ambulatory Hepatitis C Testing. J Prim Care Community Health. 2020;11:2150132720969554.
11. Kaufman HW, Bull-Otterson L, Meyer WA 3rd, et al. Decreases in Hepatitis C Testing and Treatment During the COVID-19 Pandemic. Am J Prev Med. 2021;61(3):369-376.
12. Blach S, Kondili LA, Aghemo A, et al. Impact of COVID-19 on global HCV elimination efforts. J Hepatol. 2021;74(1):31-36.
13. Buti M, Domínguez-Hernández R, Casado MA. Impact of the COVID-19 pandemic on HCV elimination in Spain. J Hepatol. 2021;74(5):1246–8.
14. Gómez L, Reygosa C, Morales-Arráez DE, et al. Diagnostic test accuracy of the cobas 6800 system for detection of hepatitis c virus viraemia levels from dried blood spots. Enferm Infecc Microbiol Clin (Engl Ed). 2020;38(6):267-274.
15. Morales-Arraez D, Hernández-Bustabad A, Medina-Alonso MJ, et al. Telemedicine and decentralized hepatitis C treatment as a strategy to enhance retention in care among people attending drug treatment centres. Int J Drug Policy. 2021;94:103235.
16. Rehman ST, Rehman H, Abid S. Impact of coronavirus disease 2019 on prevention and elimination strategies for hepatitis B and hepatitis C. World J Hepatol. 2021;13(7):781-789.
17. Frost MC, Sweek EW, Austin EJ, et al. Program Adaptations to Provide Harm Reduction Services During the COVID-19 Pandemic: A Qualitative Study of Syringe Services Programs in the U.S. AIDS Behav. 2021:1–12.
18. Blach S, Blomé M, Duberg AS, et al. Hepatitis C elimination in Sweden: Progress, challenges and opportunities for growth in the time of COVID-19. Liver Int. 2021;41(9):2024-2031.
19. Lopes H, Baptista-Leite R, Franco D, et al. Fighting Hepatitis C in a COVID-19 ecosystem. Public health policies are needed more than ever. J Gastrointestin Liver Dis. 2020;29(4):692-693.
20. Crespo J, Díaz-González Á, Iruzubieta P, et al. SARS-CoV-2 massive testing: A window of opportunity to catch up with HCV elimination. J Hepatol. 2021;74(4):966-967.
21. Giacomelli A, Pagani G, Conti F, et al. Detecting HCV infection by means of mass population SARS-CoV-2 screening: A pilot experience in Northern Italy. J Hepatol. 2021;75(2):484-486.
22. Mulchandani R, Brown B, Brooks T, et al. Use of dried blood spot samples for SARS-CoV-2 antibody detection using the Roche Elecsys ® high throughput immunoassay. J Clin Virol. 2021;136:104739.
23. Mendlowitz AB, Naimark D, Wong WWL, et al. The emergency department as a setting-specific opportunity for population-based hepatitis C screening: An economic evaluation. Liver Int. 2020;40(6):1282-1291.
24. Burgui C, Martín C, Aguinaga A, et al. Prevalence and detection of undiagnosed active hepatitis C virus infections in Navarre, Spain, 2017-2019. Rev Esp Enferm Dig. 2021;113(1):28-34. DOI: 10.17235/reed.2020.7000/2020
25. Cuadrado A, Cobo C, Mateo M, et al. Telemedicine efficiently improves access to hepatitis C management to achieve HCV elimination in the penitentiary setting. Int J Drug Policy. 2021;88:103031.
26. Mangia A, Albanese AP, Bourliére M, et al. Guidelines Have a Key Role in Driving HCV Elimination by Advocating for Simple HCV Care Pathways. Adv Ther. 2021;38(3):1397-1403.
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Citation tools
Morales-Arráez D, Benítez-Zafra F, Díaz-Flores F, Medina-Alonso M, Santiago L, Pérez-Pérez V, et all. A slowdown of hepatitis C diagnosis in high-prevalence groups and with decentralized diagnostic strategies during the COVID-19 pandemic. 8412/2021


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Publication history

Received: 20/10/2021

Accepted: 13/12/2021

Online First: 11/01/2022

Published: 03/04/2023

Article revision time: 51 days

Article Online First time: 83 days

Article editing time: 530 days


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