Year 2019 / Volume 111 / Number 2
Case Report
Healing of autoimmune hepatitis associated with hepatitis C virus infection treated with direct-acting antivirals

159-161

DOI: 10.17235/reed.2018.5528/2018

Laura López Couceiro, Elena Gómez Domínguez, Raquel Muñoz Gómez, Gregorio Castellano Tortajada, Carolina Ibarrola de Andrés, Inmaculada Fernández Vázquez,

Abstract
The use of direct-acting antivirals (DAA) for the hepatitis C virus (HCV) has yielded a significant improvement in the treatment of autoimmune hepatitis (AIH) associated with HCV infection. Interferon was the cornerstone of HCV therapy before the introduction of these agents into the clinical practice. Herein, we report the case of an HCV-infected patient who developed an interferon-induced AIH and since then, has received immunosuppressive therapy. Administration of DAA resulted in a sustained virologic response (SVR) and clinical AIH remission which allowed a discontinuation of immunosuppressive treatment.
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López Couceiro L, Gómez Domínguez E, Muñoz Gómez R, Castellano Tortajada G, Ibarrola de Andrés C, Fernández Vázquez I, et all. Healing of autoimmune hepatitis associated with hepatitis C virus infection treated with direct-acting antivirals. 5528/2018


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Publication history

Received: 09/02/2018

Accepted: 22/09/2018

Online First: 19/11/2018

Published: 01/02/2019

Article revision time: 164 days

Article Online First time: 283 days

Article editing time: 357 days


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