Year 2015 / Volume 107 / Number 12
Letter to the Editor
Recurrent drug-induced liver injury (DILI) with ciprofloxacin and amoxicillin/clavulanic

767-768

DOI: 10.17235/reed.2015.3810/2015

Luís Moreno, Jordi Sánchez Delgado, Mercedes Vergara, Meritxell Casas, Mireia Miquel, Blai Dalmau,

Abstract
Ciprofloxacin and amoxicillin/clavulanic are two widely used antibiotics due to their high efficacy and few side effects. While the percentage of hepatotoxicity of these antibiotics is low, their frequent use has led to a progressive increase in the number of cases. Both antibiotics have been associated with a wide variety of hepatotoxic reactions, from a slight rise of transaminases to fulminant hepatitis. Once hepatotoxicity secondary to a drug appears, the first step is to discontinue the drug. Physicians may opt to administer an alternative treatment with a different chemical structure. It should be borne in mind, however, that different chemical structures may also cause recurrent drug-induced liver injuries (DILI). We present the case of a patient who consecutively developed DILI due to ciprofloxacin and amoxicillin/clavulanic.
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References
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Citation tools
Moreno L, Sánchez Delgado J, Vergara M, Casas M, Miquel M, Dalmau B, et all. Recurrent drug-induced liver injury (DILI) with ciprofloxacin and amoxicillin/clavulanic . 3810/2015


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Publication history

Received: 16/04/2015

Accepted: 18/06/2015

Online First: 06/11/2015

Published: 03/12/2015

Article revision time: 61 days

Article Online First time: 204 days

Article editing time: 231 days


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