Year 2018 / Volume 110 / Number 1
Letter to the Editor
Intestinal pneumatosis and pneumoperitoneum in an oncological scenario: a change of attitude

68-69

DOI: 10.17235/reed.2017.5333/2017

Sofía de la Serna, Ana Luna, Hugo de la Rosa,

Abstract
Pneumoperitoneum and cystic intestinal pneumatosis associated to chemotherapy treatment are rare entities, with non-well stablished etiology and controversial management. We report two cases of oncological patients presenting with this complication as incidental finding in CT scan. Their course was favourable under conservative non-surgical approach associated with interruption of chemoterapy treatment.
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References
Shinagare AB, Howard SA, Krajewski KM et al. Pneumatosis intestinalis and bowel perforation associated with molecular targeted therapy: an emerging problem and the role of radiologists in its management. AJR Am J Roentgenol. 2012;199(6):1259-65.
Badgwell BD, Camp ER, Feig B et al. Management of bevacizumab-associated bowel perforation: a case series and review of the literatura. Ann Oncol. 2008;19(3):577-82
Mimatsu K, Oida T, Kawasaki A et al. Pneumatosis cystoides intestinalis after fluorouracil chemotherapy for rectal cáncer. World J Gastroenterol. 2008;14(20): 3273–3275
Thornton E, Howard SA, Jagannathan J et al. Imaging features of bowel toxicities in the setting of molecular targeted therapies in cancer patients. Br J Radiol. 2012 Oct;85(1018):1420-6
Coriat R, Ropert S, Mir O et al. Pneumatosis intestinalis associated with treatment of cancer patients with the vascular growth factor receptor tyrosine kinase inhibitors sorafenib and sunitinib. Invest New Drugs 2011;29:1090–3.
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de la Serna S, Luna A, de la Rosa H. Intestinal pneumatosis and pneumoperitoneum in an oncological scenario: a change of attitude. 5333/2017


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Publication history

Received: 24/10/2017

Accepted: 26/10/2017

Online First: 22/12/2017

Published: 12/01/2018

Article Online First time: 59 days

Article editing time: 80 days


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