Year 2025 / Volume 117 / Number 2
Letter
Secondary orofacial granulomatosis due to Crohn’s disease

119-120

DOI: 10.17235/reed.2024.10214/2023

Rodrigo Meza, Teresa Peralta, Diego Ruedi, Alex Arenas Aravena,

Abstract
We report the case of a 34-year-old female with Crohn’s disease (CD), was treated with infliximab and ileocecal resection after failure to anti-TNF. She started adalimumab for postoperative recurrence for two years, with sustained clinical and endoscopic remission. She presents with a 1.5-year history of a persistent, asymptomatic, rubbery swelling on the left half of the lower lip.
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References
1. Miest R, Bruce A, Rogers RS 3rd. Orofacial granulomatosis. Clin Dermatol. 2016 Jul-Aug;34(4):505-13. doi: 10.1016/j.clindermatol.2016.02.024. Epub 2016 Mar 3. PMID: 27343966.
2. Pathania YS. Current treatment modalities in granulomatous cheilitis. Int J Dermatol. 2022 Jun;61(6):755-759. doi: 10.1111/ijd.16126. Epub 2022 Feb 17. PMID: 35174873.
3. Phillips F, Verstockt B, Sladek M, et al. Orofacial Granulomatosis Associated with Crohn's Disease: a Multicentre Case Series. J Crohns Colitis. 2022 Mar 14;16(3):430-435. doi: 10.1093/ecco-jcc/jjab158. PMID: 34498037.
4. Phillips FM, Verstockt B, Sebastian S, et al. Inflammatory cutaneous lesions in inflammatory bowel disease treated with vedolizumab or ustekinumab: an ECCO CONFER multicentre case series. J Crohns Colitis 2020;14:1488–93.
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Meza R, Peralta T, Ruedi D, Arenas Aravena A. Secondary orofacial granulomatosis due to Crohn’s disease. 10214/2023


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Publication history

Received: 26/12/2023

Accepted: 27/12/2023

Online First: 18/01/2024

Published: 05/02/2025

Article Online First time: 23 days

Article editing time: 407 days


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