Year 2016 / Volume 108 / Number 7
Original
Spanish multicenter study to estimate the incidence of chronic pancreatitis

411-416

DOI: 10.17235/reed.2016.4056/2015

J. Enrique Domínguez Muñoz, Alfredo José Lucendo Villarín, L. Fernando Carballo Álvarez, Jose María Tenías, Julio Iglesias García,

Abstract
Objective: To estimate the incidence of chronic pancreatitis in Spain as diagnosed with endoscopic ultrasound (EUS), and to assess the risk factors and complications detected. Material and method: A descriptive, observational study of chronic pancreatitis cases diagnosed in Spanish health care centers with an EUS unit. A structured questionnaire was used to evaluate the incidence of the disease (cases identified over 18 months: from January 2011 to June 2012), risk factors, EUS criteria, Rosemont classification, and frequency of local complications. Results: Twenty-three centers were selected serving a total reference area of 14,752,704 population. During the study period 1,031 chronic pancreatitis cases were diagnosed, with an incidence of 4.66 cases per 105 inhabitants/year (95% CI: 4.65-4.67). Tobacco and alcohol use appear as risk factors in 63.8% and 66.7% of cases, respectively. Of these, 53.3% met > 5 EUS criteria for chronic pancreatitis, and 69% had findings suggestive of or consistent with chronic pancreatitis according to the Rosemont classification. Most prevalent complications included calcifications (34.7%), pseudocysts (16%), and presence of an inflammatory pancreatic tumor (10.4%). Conclusions: The incidence of chronic pancreatitis in Spain is similar to that of other European countries. Given the widespread use of the technique, EUS units are key in detecting the disease, and their activity and results allow to estimate the incidence of chronic pancreatitis over wide, representative population areas.
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Domínguez Muñoz J, Lucendo Villarín A, Carballo Álvarez L, Tenías J, Iglesias García J. Spanish multicenter study to estimate the incidence of chronic pancreatitis . 4056/2015


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Publication history

Received: 17/10/2015

Accepted: 18/03/2016

Online First: 17/06/2016

Published: 11/07/2016

Article revision time: 150 days

Article Online First time: 244 days

Article editing time: 268 days


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