Year 2020 / Volume 112 / Number 7
Original
Prevalence of hepatitis C in patients with non-affective psychotic disorders

550-554

DOI: 10.17235/reed.2020.7278/2020

Antonio Cuadrado, Joaquín Cabezas, Susana Llerena, Juan Francisco Nieves Salceda, José Ignacio Fortea, Benedicto Crespo-Facorro, Javier Crespo,

Abstract
Introduction: the goal of this study was to determine the prevalence of hepatitis C virus (HCV) infection in patients with non-affective psychotic disorders and to compare it with population-based data. Material and methods: an observational study was performed that measured anti-HCV antibodies (HCV-RNA in case of seropositivity) in 425 serum samples from patients with non-affective psychosis. Eight patients were positive for anti-HCV (1.9 %) and five had detectable HCV-RNA (1.2 %). The prevalence of viremia was significantly higher than in the general population (OR: 5.4; 95 % CI: 1.9-14.6). Conclusions: patients with non-affective psychotic disorder have a higher prevalence of active infection than that of the general population and should undergo systematic screening.
Share Button
New comment
Comments
No comments for this article
References
Razavi H. Global Epidemiology of Viral Hepatitis. Gastroenterol Clin North Am 2020;49:179-189.
2. World Health Organization, 2016b. Combating hepatitis B and C to reach elimination by 2030. . [Internet]. 2016 [consultado 2018 Oct 18]. Available from: http://apps.who.int/iris/bitstream/handle/10665/206453/WHO_HIV_2016.04_eng.pdf;jsessionid=5F7B95D01C898DF2C9C537EDF5ED25D3?sequence=1.
3. Strategic Plan for Tackling Hepatitis C in the Spanish National Health System. Ministry of Health, Social Services and Equality. [Internet]. 2015 [consultado 2018 Dec 18]. Available from: http://www.easl.eu/medias/files/eu/PEAHC_v2_eng.pdf. 2015.
4. Prevalencia de la infección por hepatitis C en población general en España (2017-2018). Resultados del 2º Estudio de Seroprevalencia en España (2017-2018) [Internet]. 2019 [consultado 2020 Feb 20]. Available from: https://www.mscbs.gob.es/ciudadanos/enfLesiones/enfTransmisibles/sida/docs/INFORME_INFECCION_VHC_ESPANA2019.pdf.
5. Carvalho-Gomes A, Cubells A, Pallares C, et al. A population-based screening for hepatitis C antibodies and active infection using a point-of-care test in a low prevalence area. PLoS One 2020;15:e0228351.
6. Crespo J, Cuadrado A, Perello C, et al. Epidemiology of hepatitis C virus infection in a country with universal access to direct-acting antiviral agents: data for designing a cost-effective elimination policy in Spain. J Viral Hepat 2019.
7. Estrategia para la eliminación de la hepatitis C en Cantabria. Servicio Cántabro de Salud. Consejería de Sanidad. Gobierno de Cantabria. [Internet]. 2019 [consultado 2019 May 19]. Available from: http://www.scsalud.es/documents/2162705/2163013/Estrategia_eliminacion_Hepatitis_C.pdf/235888b7-589e-b41d-089c-e4ee0ff04d25. 2019.
8. Cuadrado A, Llerena S, Cobo C, et al. Microenvironment Eradication of Hepatitis C: A Novel Treatment Paradigm. Am J Gastroenterol 2018;113:1639-1648.
9. Ayano G, Tulu M, Haile K, et al. A systematic review and meta-analysis of gender difference in epidemiology of HIV, hepatitis B, and hepatitis C infections in people with severe mental illness. Ann Gen Psychiatry 2018;17:16.
10. Pelayo-Teran JM, Gajardo-Galan V, Gomez-Revuelta M, et al. Duration of active psychosis and functional outcomes in first-episode non-affective psychosis. Eur Psychiatry 2018;52:29-37.
11. Domenech JM, Granero R. SPSS Macro !CI2IP Confidence intervals for measures of association, Macro call for Cross-sectional study [computer program]. Bellaterra: University Autónoma de Barcelona; 2006. [Internet]. 2006 [consultado 2019 Dec 19]. Available from: http://www.metodo.uab.cat/macros.htm.
12. Hughes E, Bassi S, Gilbody S, et al. Prevalence of HIV, hepatitis B, and hepatitis C in people with severe mental illness: a systematic review and meta-analysis. Lancet Psychiatry 2016;3:40-48.
13. Bauer-Staeb C, Jorgensen L, Lewis G, et al. Prevalence and risk factors for HIV, hepatitis B, and hepatitis C in people with severe mental illness: a total population study of Sweden. Lancet Psychiatry 2017;4:685-693.
14. Freudenreich O, Gandhi RT, Walsh JP, et al. Hepatitis C in schizophrenia: screening experience in a community-dwelling clozapine cohort. Psychosomatics 2007;48:405-11.
15. Crespo J, Albillos A, Buti M, et al. Elimination of hepatitis C. Positioning document of the Spanish Association for the Study of the Liver (AEEH). Rev Esp Enferm Dig. 2019;111(11):862‐873. doi:10.17235/reed.2019.6700/2019
Related articles

Editorial

Cases of liver disease lost in the health system: a call to action

DOI: 10.17235/reed.2021.8316/2021

Original

Active search for hepatitis C patients in primary care

DOI: 10.17235/reed.2021.8067/2021

Original

Hepatitis C in homeless people: reaching a hard-to-reach population

DOI: 10.17235/reed.2021.7737/2020

Editorial

Screening guide for hepatitis C virus infection in Spain

DOI: 10.17235/reed.2020.7728/2020

Special Article

Strategy for the Elimination of Hepatitis C in Cantabria

DOI: 10.17235/reed.2020.7108/2020

Editorial

Reflex testing. A key tool for the elimination of hepatitis C

DOI: 10.17235/reed.2020.7201/2020

Original

Quality of life study in asymptomatic patients with hepatitis C

DOI: 10.17235/reed.2019.6339/2019

Letter

Acute seronegative hepatitis C: two case reports

DOI: 10.17235/reed.2019.5921/2018

Letter

Dyspepsia, functional dyspepsia and Rome IV criteria

DOI: 10.17235/reed.2018.5599/2018

Citation tools
Cuadrado A, Cabezas J, Llerena S, Nieves Salceda J, Fortea J, Crespo-Facorro B, et all. Prevalence of hepatitis C in patients with non-affective psychotic disorders. 7278/2020


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 1079 visits.
This article has been downloaded 187 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 18/05/2020

Accepted: 01/06/2020

Online First: 24/06/2020

Published: 08/07/2020

Article revision time: 6 days

Article Online First time: 37 days

Article editing time: 51 days


Share
This article has been rated by 1 readers.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology