Year 2018 / Volume 110 / Number 8
Digestive Diseases Image
Painless jaundice as an initial presentation of lung adenocarcinoma

520-521

DOI: 10.17235/reed.2018.5587/2018

Irene Andaluz García, Irene González Partida, Javier Lucas Ramos, Jorge Yebra Carmona,

Abstract
Malignant bile duct obstruction is a common entity in clinical practice and is infrequently caused by non-biliopancreatic neoplasms. We report the case of a male admitted with malignant obstruction of the biliary tract, showing after numerous studies that this obstruction was the initial presentation of a stage IV adenocarcinoma of the lung. Pulmonary neoplasms have variable behaviors being often spread at time of diagnosis, especially in the more aggressive subtypes. However, it is uncommon its manifestation as obstructive jaundice and when this happens it is usually due to liver damage and not to metastases to periampullary region that are extremely infrequent. In this case, the role of pathological anatomy and immunohistochemistry was essential in identifying the origin of the tumor and starting targeted treatment, since the clinical presentation and usual laboratory and image tests did not allow to differentiate it from a primary cholangiocarcinoma.
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References
Cha IH, Kim JN, Kim YS, et al. Metastatic common bile duct cancer from pulmonary adenocarcinoma presenting as obstructivejaundice. Korean J Gastroenterol. 2013;61(1):50–53
Pericleous, S., Mukherjee, S. & Hutchins, R. R. Lung adenocarcinoma presenting as obstructive jaundice : a case report and review of literature. World Journal of Surgical Oncology 2008, 6:120
Yu, C., Yu, C., Nai, C. et al. Case Report A presenting with obstructive jaundice in pulmonary adenocarcinoma: a case report. Int J Clin Exp Med 2015;8(7):11613-11616
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Andaluz García I, González Partida I, Lucas Ramos J, Yebra Carmona J. Painless jaundice as an initial presentation of lung adenocarcinoma. 5587/2018


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Publication history

Received: 09/03/2018

Accepted: 15/03/2018

Online First: 23/07/2018

Published: 30/07/2018

Article Online First time: 136 days

Article editing time: 143 days


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