Year 2025 / Volume 117 / Number 2
Letter
Endoscopic spraying of smectite to prevent esophageal stricture after endoscopic submucosal dissection

118-119

DOI: 10.17235/reed.2024.10203/2023

Zaman Swapnil, Jiankun Wang, Kexin He, Li Liu, Zhining Fan,

Abstract
Esophageal stenosis after ESD has been recorded high for large-scale esophageal lesion. Risk factors for increasing the occurrence of stenosis includes long type lesions, lesions infiltrating into the muscularis mucosa and muscular layer injury. In this case, postoperative stricture of the patient was highly likely occurred. Smectite is a mucosal protective agent that can resist external stimuli, promote wound healing, and reduce inflammatory factors. Therefore, it can effectively prevent the formation of scars on wounds. This study was carried out in humans for the first time and was successful. In conclusion, endoscopic spraying of smectite may be effective and safe in preventing esophageal stenosis after ESD with large non-circumferential lesions.
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References
[1] Zhang Y, Zhang B, Wang Y, et al. Advances in the Prevention and Treatment of Esophageal Stricture after Endoscopic Submucosal Dissection of Early Esophageal Cancer. J Transl Int Med 2020;8:135-145.
[2] Shi Q, Ju H, Yao LQ, et al. Risk factors for postoperative stricture after endoscopic submucosal dissection for superficial esophageal carcinoma. Endoscopy. 2014;46:640-644.
[3] Ishihara R. Prevention of esophageal stricture after endoscopic resection. Dig Endosc. 2019;31:134-145.
[4] Wang J, Wang M, Zhao L, et al. Investigating the efficacy and safety of mineral smectite granules on wound healing. Exp Ther Med 2021;21:160.
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Swapnil Z, Wang J, He K, Liu L, Fan Z. Endoscopic spraying of smectite to prevent esophageal stricture after endoscopic submucosal dissection. 10203/2023


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Publication history

Received: 23/12/2023

Accepted: 27/12/2023

Online First: 18/01/2024

Published: 05/02/2025

Article Online First time: 26 days

Article editing time: 410 days


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