Year 2020 / Volume 112 / Number 7
Original
Vedolizumab response in inflammatory bowel disease. Two years of follow-up

555-558

DOI: 10.17235/reed.2020.7130/2020

Pilar del Pino Bellido, María Belvis Jiménez, Luisa Castro Laria, María Belén Maldonado Pérez, Antonia Sáez Díaz, Ángel Caunedo Álvarez, Federico Argüelles-Arias,

Abstract
Background: vedolizumab is an α4β7 integrin antagonist. The aim of this study was to evaluate the clinical response and remission rates with vedolizumab. Methods: this was a retrospective study of inflammatory bowel disease (IBD) patients who received vedolizumab between 2016 and 2019. Response and remission rates were analyzed at three, six, 12, 18 and 24 months after induction. Results: fifty-five patients were included. Clinical remission rates in CD and UC at three, six, 12, 18 and 24 months were 19.35 %, 26.67 %, 30.43 %, 30 %, 38.89 % and 29.17 %, 26.09 %, 19.05 %, 26.67 % and 20 %, respectively. Conclusions: vedolizumab is effective for induction and maintenance of clinical remission, both in Crohn’s disease and ulcerative colitis.
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del Pino Bellido P, Belvis Jiménez M, Castro Laria L, Maldonado Pérez M, Sáez Díaz A, Caunedo Álvarez Á, et all. Vedolizumab response in inflammatory bowel disease. Two years of follow-up. 7130/2020


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Publication history

Received: 13/04/2020

Accepted: 04/06/2020

Online First: 24/06/2020

Published: 08/07/2020

Article revision time: 50 days

Article Online First time: 72 days

Article editing time: 86 days


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