Year 2020 / Volume 112 / Number 3
Letter
Lymphoepithelioma-like carcinoma of the duodenum: a very infrequent tumor

239

DOI: 10.17235/reed.2020.6503/2019

Marta Chaparro Mirete, Víctor López-López, Ricardo Robles Campos,

Abstract
Lymphoepithelioma-like carcinoma (LELC) is a type of tumor that is histologically characterized by wide lymphoplasmacytic infiltration in the stroma. This type of carcinoma is usually found in the airway and is extremely infrequent in the gastrointestinal tract. We present the case of a 77-year-old male, under follow-up for refractory anemia, who was diagnosed with a cavum type lymphoepithelioma-like carcinoma in the third duodenal portion. After diagnosis, he was treated surgically via a duodenal resection, without adjuvant oncological treatment due to the early diagnosis and surgical pathology features. Today, 12 months after surgery, the patient is free of disease. Cases of LELC have been described in other organs of the gastrointestinal tract. However, after an extensive review of the literature, this is the first case of LELC in the duodenum. A review of the available literature about LELC in the digestive tract and its management was also included.
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References
1. Zhang S, Cui Y, Zhong B, et al. Clinicopathological characteristics and survival analysis of primary duodenal cancers: a 14-year experience in a tertiary centre in South China. Int J of Colorectal Dis 2010;26:219-226
2. Shinoda M, Kadota Y, Tsujikawa H, et al. Lympho- epithelioma-like hepatocellular carcinoma: a case report and a review of the literature. World J Surg Oncol 2013; 11: 97.
3. Xue J, Yu H, Yan J, et al. Non-Epstein-Barr virus-associated double primary lymphoepithelioma-like carcinoma of the esophagus and stomach: a case report and literature review. Int J Clin Exp Med. 2015;8:10051–10057.
4. Díaz del Arco C, Esteban Collazo F, Fernández Aceñero M. Lymphoepithelioma-like carcinoma of the large intestine: A case report and literature review. Rev Esp Patol 2018;51:18-22
5. Kon S, Kasai K, Tsuzuki N, et al. Lymphoepithelioma-like Carcinoma of Rectum: Possible Relation with EBV. Pathol Res Pract 2001;197:577-582.
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Chaparro Mirete M, López-López V, Robles Campos R. Lymphoepithelioma-like carcinoma of the duodenum: a very infrequent tumor. 6503/2019


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Publication history

Received: 14/07/2019

Accepted: 31/07/2019

Online First: 05/02/2020

Published: 05/03/2020

Article Online First time: 206 days

Article editing time: 235 days


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